Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | 100 E Rich St | 1116 Woodruff Rd | No tags | ||||
Greyhound + FlixBus | Bus | Columbus Bus Station | 1116 Woodruff Rd | No tags | ||||
 | Bus | Columbus Bus Station | 1116 Woodruff Rd | No tags | ||||
| Bus | Columbus Bus Station | 1116 Woodruff Rd | No tags | ||||
Greyhound + FlixBus | Bus | Columbus Bus Station | 1116 Woodruff Rd | No tags |
Get from Columbus to Greenville
The journey takes about 21 hours 30 minutes, and with fares starting at just R 1 812, it presents an excellent value for a comfortable ride.
Compare bus companies
Where are the popular stops in Columbus and Greenville?
Frequently asked questions about travelling from Columbus, OH to Greenville, SC by bus
How much does a bus ticket from Columbus to Greenville cost?
The bus ticket price from Columbus to Greenville starts at R 1 812. The best way to find cheap bus tickets from Columbus to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Columbus to Greenville?
The average travel time between Columbus and Greenville is around 21h 30m, although the fastest bus will take about 13h 45m. This is the time it takes to travel the 572 km that separates the two cities.
How many daily bus connections are there between Columbus and Greenville?
The number of buses from Columbus to Greenville can differ depending on the day of the week. On average, there are 5 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Columbus to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Columbus to Greenville?
When taking the bus from Columbus to Greenville, you can travel comfortably and safely with Greyhound, FlixBus.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbus, OH to Greenville, SC was searched and found on 24 Nov 2025 with a price of R 2 083To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus, OH to Greenville, SC as early as possible.
You can expect to pay from R 2 083 to R 2 109 for a bus ticket from Columbus, OH to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 083, which is on 2025-11-24.
