Find coaches from Columbus, OH to Greenville, SC

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Tomorrow12 Jul
from US$159
Sun13 Jul
Mon14 Jul
Tue15 Jul
Wed16 Jul
Thu17 Jul
Fri18 Jul
Sat19 Jul

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 12 July at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: 13 July at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 12 July at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: 12 July at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 July at
    Departure city: Columbus
    Departure location: 100 E Rich St
    Arrival time: 13 July at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 July at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: 12 July at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 July at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: 13 July at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Bus Columbus to Greenville: Trip Overview

Average ticket priceUS$136
Average bus trip duration21h 45m
Number of daily buses5
Earliest bus departure00:45
Distance356 miles
Latest bus departure23:15

Columbus to Greenville Bus

Busbud helps you find a bus from Columbus to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Columbus to Greenville from the most reliable bus companies operating this trip.

Discover how much the bus trip from Columbus to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Columbus, OH - Greenville, SC

  1. What's the distance between Columbus and Greenville by coach?

    The journey from Columbus to Greenville by coach covers an approximate distance of 355 miles (572 km).

  2. How can I travel from Columbus to Greenville avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/07
No data
10/07
No data
Today
No data
12/07
US$151
13/07
No data
14/07
No data
15/07
No data
16/07
No data
busbud logoThe cheapest trip from Columbus to Greenville was searched and found on 12 Jul 2025 with a price of US$151

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus to Greenville as early as possible.

You can expect to pay from US$151 to US$178 for a bus ticket from Columbus to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at US$151, which is on 2025-07-12.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Columbus and Greenville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Columbus to Greenville, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Columbus to Greenville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Columbus to Greenville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Columbus by bus?

Bus from Columbus to Greenville

Why choose Busbud?

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