Find coaches from Columbus, OH to St. Louis

Next departures

Next departures from Columbus to St. Louis on 4 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Columbus (E Mound St)
    		Gateway StationCheapest
    Greyhound Lines, Inc.
      		Columbus (E Mound St)
      		Gateway StationFastest
      Greyhound Lines, Inc.
        		Columbus (E Mound St)
        		Gateway StationNo tags

        Last refresh of the prices: Last Wednesday at 11:21 AM EDT.

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        Get from Columbus to St. Louis

        This route is served by bus only

        The journey takes about 11 hours 30 minutes, and with fares starting at just US$50, it presents an excellent value for a comfortable ride.

        4bus per day
        11h 30mAverage duration
        638 kmDistance
        16kgCO₂ emissions

        Bus Columbus, OH to St. Louis: Trip Overview

        Average ticket priceUS$74
        Average bus trip duration11h 30m
        Number of daily buses4
        Earliest bus departure03:50
        Distance637 km
        Latest bus departure23:30

        Columbus to St. Louis Bus

        Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Columbus to St. Louis.

        Bus service from Columbus to St. Louis will be provided by the most trusted bus companies.

        Discover how much the bus trip from Columbus to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

        Frequently asked questions on the trip Columbus, OH - St. Louis

        1. How much does a bus ticket from Columbus to St. Louis cost?

          The bus ticket price from Columbus to St. Louis starts at US$50. The best way to find cheap bus tickets from Columbus to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

        2. How long is the bus ride from Columbus to St. Louis?

          The average travel time between Columbus and St. Louis is around 11h 30m, although the fastest bus will take about 9h 20m. This is the time it takes to travel the 638 km that separates the two cities.

        3. How many daily bus connections are there between Columbus and St. Louis?

          The number of buses from Columbus to St. Louis can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Columbus to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.

        4. Which bus companies travel from Columbus to St. Louis?

          When taking the bus from Columbus to St. Louis, you can travel comfortably and safely with Greyhound, FlixBus.

        Find cheapest prices for buses

        Price is for a one-way ticket for one passenger and based on past searches.

        Best price found
        01/11
        US$60
        02/11
        US$55
        Today
        US$50
        04/11
        US$55
        05/11
        No data
        06/11
        No data
        07/11
        No data
        08/11
        No data
        busbud logoThe cheapest trip from Columbus, OH to St. Louis was searched and found on 03 Nov 2025 with a price of US$50

        To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus, OH to St. Louis as early as possible.

        You can expect to pay from US$50 to US$150 for a bus ticket from Columbus, OH to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$55, which is on 2025-11-04.

        About Bus Travel

        Bus Travel Tips

        If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Columbus to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

        Much more than a mere vehicle taking you from Columbus to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

        Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Columbus to St. Louis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

        Make a music playlist for your bus ride from Columbus to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

        Did you know?

        Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

        The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

        It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

        Will you be returning to Columbus, OH by bus?

        Bus from St. Louis to Columbus, OH

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