Find coaches from Columbus, OH to St. Louis

Find affordable coach tickets from Columbus, OH to St. Louis with flexible options. Book your journey now

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Today9 Jul
from US$70
Tomorrow10 Jul
from US$65
Fri11 Jul
from US$65
Sat12 Jul
from US$65
Sun13 Jul
from US$65
Mon14 Jul
from US$65
Tue15 Jul
from US$61
Wed16 Jul

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 10 July at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: 10 July at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 10 July at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: 11 July at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 10 July at
    Departure city: Columbus
    Departure location: 100 E Rich St
    Arrival time: 10 July at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 10 July at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: 10 July at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 10 July at
    Departure city: Columbus
    Departure location: 100 E Rich St
    Arrival time: 11 July at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Bus Columbus to St. Louis: Trip Overview

Average ticket priceUS$70
Average bus trip duration11h 30m
Number of daily buses4
Earliest bus departure04:50
Distance396 miles
Latest bus departure23:30

Columbus to St. Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Columbus to St. Louis.

Bus service from Columbus to St. Louis will be provided by the most trusted bus companies.

Discover how much the bus trip from Columbus to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Columbus, OH - St. Louis

  1. What's the distance between Columbus and St. Louis by coach?

    The distance between Columbus and St. Louis by coach is approximately 396 miles (638 km).

  2. How can I travel from Columbus to St. Louis avoiding air travel?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/07
US$58
08/07
US$57
Today
US$62
10/07
US$57
11/07
US$57
12/07
US$57
13/07
US$57
14/07
US$57
busbud logoThe cheapest trip from Columbus to St. Louis was searched and found on 8 Jul 2025 with a price of US$57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus to St. Louis as early as possible.

You can expect to pay from US$57 to US$121 for a bus ticket from Columbus to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$57, which is on 2025-07-10.

Usually FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Columbus to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Columbus to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Columbus to St. Louis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Columbus to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Columbus by bus?

Bus from Columbus to St. Louis

Why choose Busbud?

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