Find coaches from Detroit, MI to St. Louis

Next departures

Next departures from Detroit to St. Louis on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Detroit Bus Station
Gateway StationCheapest
Greyhound Lines, Inc. + FlixBus
Detroit Bus Station
Gateway StationFastest
Greyhound Lines, Inc. + FlixBus
Detroit Bus Station
Gateway StationNo tags

Last refresh of the prices: Today at 7:17 AM EDT.

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Compare 2 ways to travel from Detroit to St. Louis

busbud logoWe recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 13 hours 41 minutes and with fares starting at just US$75, it presents an excellent value for a comfortable ride.

1train per day
13h 41mAverage duration
733 kmDistance
67kgCO₂ emissions
Bus
Average priceUS$50 - US$205Average duration15h 50m
18kg CO₂e
Train
Average priceUS$75 - US$506Average duration13h 41m
67kg CO₂e

Bus Detroit, MI to St. Louis: Trip Overview

Average ticket priceUS$92
Average bus trip duration15h 50m
Number of daily buses3
Earliest bus departure06:40
Distance731 km
Latest bus departure23:25

Detroit to St. Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Detroit to St. Louis.

We make sure you can find a bus service from Detroit to St. Louis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Detroit, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Detroit, MI - St. Louis

  1. How much does a bus ticket from Detroit to St. Louis cost?

    The bus ticket price from Detroit to St. Louis starts at US$50. The best way to find cheap bus tickets from Detroit to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Detroit to St. Louis?

    The average travel time between Detroit and St. Louis is around 15h 50m, although the fastest bus will take about 14h 5m. This is the time it takes to travel the 733 km that separates the two cities.

  3. How many daily bus connections are there between Detroit and St. Louis?

    The number of buses from Detroit to St. Louis can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Detroit to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Detroit to St. Louis?

    When taking the bus from Detroit to St. Louis, you can travel comfortably and safely with Greyhound, FlixBus.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$96
29/10
US$96
Today
US$111
31/10
US$104
01/11
US$90
02/11
US$81
03/11
US$63
04/11
US$83
busbud logoThe cheapest trip from Detroit, MI to St. Louis was searched and found on 03 Nov 2025 with a price of US$63

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to St. Louis as early as possible.

You can expect to pay from US$63 to US$133 for a bus ticket from Detroit, MI to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$63, which is on 2025-11-03.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Detroit to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to St. Louis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Detroit to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Detroit to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Detroit, MI to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Detroit, MI by bus?

Bus from St. Louis to Detroit, MI

You can also go to St. Louis by train

Train from Detroit, MI to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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