Find coaches from Durham, NC, US to Louisville

Next departures

Next departures from Durham to Louisville on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Durham Greyhound Bus Station
Louisville, KYCheapestFastest
FlixBus + Greyhound Lines, Inc.
Durham Greyhound Bus Station
Louisville, KYNo tags

Last refresh of the prices: Yesterday at 9:28 PM EDT.

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Get from Durham to Louisville

busbud logoThis route is served by bus only

The journey takes about 18 hours 25 minutes, and with fares starting at just US$105, it presents an excellent value for a comfortable ride.

5bus per day
18h 25mAverage duration
659 kmDistance
16kgCO₂ emissions

Bus Durham, NC, US to Louisville: Trip Overview

Average ticket priceUS$157
Average bus trip duration18h 25m
Number of daily buses5
Earliest bus departure01:10
Distance658 km
Latest bus departure22:05

Durham to Louisville Bus

With Busbud, comparing and booking tickets for a bus from Durham to Louisville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Durham to Louisville from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Durham to Louisville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Durham, NC, US - Louisville

  1. How much does a bus ticket from Durham to Louisville cost?

    The bus ticket price from Durham to Louisville starts at US$105. The best way to find cheap bus tickets from Durham to Louisville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Durham to Louisville?

    The average travel time between Durham and Louisville is around 18h 25m, although the fastest bus will take about 16h 50m. This is the time it takes to travel the 659 km that separates the two cities.

  3. How many daily bus connections are there between Durham and Louisville?

    The number of buses from Durham to Louisville can differ depending on the day of the week. On average, there are 5 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Durham to Louisville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Durham to Louisville?

    When taking the bus from Durham to Louisville, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Durham to Louisville?

    Buses travelling between Durham and Louisville leave from Durham Greyhound Bus Station or Compare Foods Durham and arrive at Louisville Greyhound Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/10
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30/10
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Today
US$118
01/11
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02/11
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03/11
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04/11
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busbud logoThe cheapest trip from Durham, NC, US to Louisville was searched and found on 31 Oct 2025 with a price of US$118

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Louisville as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Durham to Louisville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Durham to Louisville, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Durham to Louisville that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Louisville while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Durham, NC, US by bus?

Bus from Louisville to Durham, NC, US

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