Find coaches from Florence, SC, US to Boston, MA, US

Next departures

Next departures from Florence to Boston on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus station
151 Steel Pl, CambridgeCheapest
FlixBus + Greyhound Lines, Inc.
Florence, SC
Boston (South Station)Fastest
FlixBus + Greyhound Lines, Inc.
Bus station
Boston (South Station)No tags
FlixBus
Florence, SC
BrooklineNo tags
FlixBus + Greyhound Lines, Inc.
Florence, SC
Boston (South Station)No tags

Last refresh of the prices: Today at 1:55 AM EDT.

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Compare 2 ways to travel from Florence to Boston

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Boston. The journey takes about 1 day, 3 hours 5 minutes and with fares starting at just US$103, it presents an excellent value for a comfortable ride.

4bus per day
1d 3hAverage duration
1182 kmDistance
30kgCO₂ emissions
Average priceUS$103 - US$318Average duration1d 3h
30kg CO₂e
Average priceUS$138 - US$660Average duration19h 32m
108kg CO₂e

Bus Florence, SC, US to Boston, MA, US: Trip Overview

Average ticket priceUS$164
Average bus trip duration1d 3h
Number of daily buses4
Earliest bus departure00:05
Distance1182 km
Latest bus departure16:15

Florence to Boston Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Boston.

We make sure you can find a bus service from Florence to Boston from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Florence to Boston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Florence, SC, US - Boston, MA, US

  1. How much does a bus ticket from Florence to Boston cost?

    The bus ticket price from Florence to Boston starts at US$103. The best way to find cheap bus tickets from Florence to Boston is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Florence to Boston?

    The average travel time between Florence and Boston is around 1d 3h, although the fastest bus will take about 18h 45m. This is the time it takes to travel the 1176 km that separates the two cities.

  3. How many daily bus connections are there between Florence and Boston?

    The number of buses from Florence to Boston can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Florence to Boston by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Florence to Boston?

    When taking the bus from Florence to Boston, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Florence to Boston?

    Buses travelling between Florence and Boston leave from Florence Bus Station or TA Travel Center - Florence and arrive at Back Bay Station, South Station, North Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
No data
29/10
No data
Today
US$97
31/10
US$270
01/11
No data
02/11
No data
03/11
No data
04/11
No data
busbud logoThe cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on 30 Oct 2025 with a price of US$97

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US as early as possible.

You can expect to pay from US$97 to US$270 for a bus ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$270, which is on 2025-10-31.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Boston but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florence to Boston, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Boston that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Boston while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Florence, SC, US to Boston, MA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence, SC, US by bus?

Bus from Boston, MA, US to Florence, SC, US

You can also go to Boston, MA, US by train

Train from Florence, SC, US to Boston, MA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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