Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus
| Bus station | Brookline | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Florence, SC | Boston (South Station) | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Florence, SC | Boston (South Station) | No tags | ||||
 | Bus
| Florence, SC | 151 Steel Pl, Cambridge | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Florence, SC | Brookline | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Bus station | Boston (South Station) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Bus station | Boston (South Station) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Bus station | 151 Steel Pl, Cambridge | No tags |
Last refresh of the prices: Yesterday at 10:58 AM EDT.
Compare 2 ways to travel from Florence to Boston
Among the sustainable travel choices, the Bus stands out as a good way to reach Boston. The journey takes about 1 day and with fares starting at just ₪264, it presents an excellent value for a comfortable ride.
Bus stations and stops in Florence and Boston
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Boston
- A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA - B
North Station
100 Legends Way, Boston, MA 02114, USA - C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Compare bus companies
Frequently asked questions about travelling from Florence, SC, US to Boston, MA, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Florence to Boston?
The cheapest bus tickets from Florence to Boston start at ₪264. The average price for this route is around ₪349. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Florence to Boston?
The average bus journey time from Florence to Boston is 1d , covering a distance of 1181 km. The fastest bus gets you there in 19h 15m and is operated by FlixBus.
Which bus companies service the Florence to Boston route?
What is the earliest and latest departure time for the bus from Florence to Boston?
The earliest bus departs from Florence to Boston at 00:05. And the latest bus departs at 19:20.
What are the CO₂ emissions for the bus trip from Florence to Boston?
A bus trip from Florence to Boston produces an estimated 29.523799999999998 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Florence to Boston?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 15731 reviews.
Which bus company has the best Wi-Fi from Florence to Boston?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Florence to Boston?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Florence to Boston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on 15 Sept 2026 with a price of ₪223To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US as early as possible.
You can expect to pay from ₪223 to ₪541 for a bus ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at ₪241, which is on 2026-09-22.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Florence, SC, US to Boston, MA, US?
The Bus is the cheapest travel choice for this destination
