Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus station | Boston (South Station) | No tags | ||||
FlixBus + Greyhound | Bus | Bus station | 151 Steel Pl, Cambridge | No tags | ||||
Greyhound + FlixBus | Bus | Bus station | 151 Steel Pl, Cambridge | No tags | ||||
| Bus | Bus station | Boston (South Station) | No tags | ||||
| Bus | Bus station | Boston (South Station) | No tags |
Compare 2 ways to go from Florence to Boston
Among the sustainable travel choices, the train stands out as a good way to reach Boston. The journey takes about 19 hours 32 minutes, and with fares starting at just $206, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Boston?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C700 Atlantic Ave, Boston, MA 02205, USA
- D
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - E
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - F
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
Compare bus companies
Frequently asked questions about travelling from Florence, SC, US to Boston, MA, US by bus
How much does a bus ticket from Florence to Boston cost?
The bus ticket price from Florence to Boston starts at $145. The best way to find cheap bus tickets from Florence to Boston is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Florence to Boston?
The average travel time between Florence and Boston is around 1d 2h, although the fastest bus will take about 18h 45m.This is the time it takes to travel the 1176 km that separates the two cities.
How many daily bus connections are there between Florence and Boston?
The number of buses from Florence to Boston can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Florence to Boston by comparing and selecting the bus that fits you travel style and budget on Busbud.
Which bus companies travel from Florence to Boston?
When taking the bus from Florence to Boston, you can travel comfortably and safely with FlixBus, Greyhound.
What are the departure and arrival stations when taking the bus from Florence to Boston?
Buses travelling between Florence and Boston leave from Florence Bus Station or TA Travel Center - Florence and arrive at Back Bay Station, North Station, South Station.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Nov 25, 2025 with a price of $188To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US, as early as possible.
You can expect to pay from $188 to $358 for a bus ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $188 which is on 2025-11-25.
What's the cheapest way to go from Florence, SC, US to Boston, MA, US?
The bus is the cheapest travel choice for this destination
