Bus Tickets from Florence, SC to Boston, MA

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TodayMay 21
TomorrowMay 22
FriMay 23
from US$174
SatMay 24
SunMay 25
from US$187
MonMay 26
TueMay 27
WedMay 28

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 23 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: May 25 at
    Destination city: Boston
    Destination location: Boston
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 23 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: May 24 at
    Destination city: Boston
    Destination location: Boston (South Station)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: May 24 at
    Destination city: Boston
    Destination location: Boston (South Station)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: May 24 at
    Destination city: Boston
    Destination location: Boston (South Station)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: May 24 at
    Destination city: Boston
    Destination location: 151 Steel Pl, Cambridge
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Friday at 4:17 AM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Florence to Boston

Bus
Average PriceUS$131 - US$237Average Duration1d 5h
30kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$164 - US$471Average Duration19h 32m
107kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Florence to Boston

Among the sustainable travel choices, the train stands out as a good way to reach Boston. The journey takes about 19 hours 32 minutes, and with fares starting at just US$164, it presents an excellent value for a comfortable ride.

6train per day
19h 32mAverage Duration
US$164Cheapest ticket
107kgCO₂ emissions

Bus Florence to Boston: Trip Overview

Average Ticket PriceUS$170
Average Bus Trip Duration1d 5h
Number of daily buses4
Earliest bus departure5:35am
Distance1182 km
Latest bus departure11:59pm

Florence to Boston Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Boston.

We make sure you can find a bus service from Florence to Boston from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Florence to Boston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Florence - Boston

  1. How long does it take to get to Boston from Florence by bus?

    The trip from Florence to Boston will take on average 1d 5h. The fastest bus on this trip will get to Boston in 18h 51m

  2. What is the distance between Florence and Boston?

    It's about 1176 km (729 miles) from Florence to Boston.

  3. What are the departure and arrival locations for buses traveling from Florence to Boston?

    Buses departing from Florence Bus Station in Florence will take you to South Station in Boston.

  4. What is the cheapest way to travel from Florence to Boston?

    Taking the bus is the most budget-friendly option to travel from Florence to Boston. With a starting ticket price of US$131, this bus becomes your top pick for this journey.

  5. How much is the bus from Florence to Boston?

    You can expect to pay around US$170 for the bus ride from Florence to Boston.

  6. Is it possible to travel by overnight bus from Florence to Boston?

    Yes! If you're heading from Florence to Boston, you'll find buses departing until 11:59pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-19
US$140
05-20
No data
Today
No data
05-22
No data
05-23
US$167
05-24
No data
05-25
US$230
05-26
No data
busbud logoThe cheapest trip from Florence to Boston was searched and found on May 19, 2025 with a price of US$140

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Boston, as early as possible.

You can expect to pay from US$140 to US$230 for a bus ticket from Florence to Boston based on the last 2 days. You can expect to find the cheapest price for the trip at US$167 which is on 2025-05-23.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Boston but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florence to Boston, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Boston that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Boston while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Florence to Boston?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence by bus?

Bus from Florence to Boston

You can also go to Boston by train

Train from Florence to Boston

Why choose Busbud?

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