Next bus departures

Next departures for Florence to Boston on July 31
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	7:20pm	Bus station	19h 50m	3:10pm	Boston (South Station)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	12:05am	Florence, SC	18h 45m	6:50pm	Boston (South Station)	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	5:45am	Florence, SC	1d 6h	12:00pm	Boston (South Station)	No tags
	Bus	12:05am	Florence, SC	1d 5h	5:40am	Brookline	No tags
	Bus	12:05am	Florence, SC	19h 15m	7:20pm	151 Steel Pl, Cambridge	No tags
Greyhound Lines, Inc. + FlixBus	Bus	3:20pm	Bus station	20h 40m	12:00pm	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:20pm	Bus station	1d 10h	5:40am	Brookline	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:20pm	Bus station	1d	7:20pm	151 Steel Pl, Cambridge	No tags

Last refresh of the prices: Yesterday at 12:34 AM EDT.

Compare 2 ways to go from Florence to Boston

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Boston. The journey takes about 22 hours 45 minutes, and with fares starting at just COP 251,460, it presents an excellent value for a comfortable ride.

6bus per day

22h 45mAverage Duration

1181 kmDistance

30kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCOP 251,460 - COP 1,014,303	Average Duration22h 45m	CO₂ emissions 30kg CO₂e
Train	Average PriceCOP 482,806 - COP 2,598,424	Average Duration20h 32m	CO₂ emissions 107kg CO₂e

Bus stations and stops in Florence and Boston

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Boston

A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA
Visit page
B
North Station
100 Legends Way, Boston, MA 02114, USA
Visit page
C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA
D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA

Compare bus companies

FlixBus

3.5/513,072 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

Greyhound

3.5/587,587 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

Wi‑Fi2.5

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Adirondack Trailways

Frequently asked questions about travelling from Florence, SC, US to Boston, MA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Florence to Boston?
The cheapest bus tickets from Florence to Boston start from COP 251,460. The average price for this route is around COP 382,702. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Boston?
The average bus travel time from Florence to Boston is 22h 45m, covering a distance of 1181 km. The quickest bus can get you there in 19h 15m and is operated by FlixBus.
Which bus companies service the Florence to Boston route?
Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, Greyhound.
What are the earliest and latest departure times for the bus from Florence to Boston?
The earliest bus departs from Florence to Boston at 12:05am. And the latest bus departs at 7:20pm.
What are the CO₂ emissions for the bus trip from Florence to Boston?
A bus trip from Florence to Boston generates an estimated 29.5223 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Florence to Boston?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 13066 reviews.
Which bus company has the best Wi-Fi from Florence to Boston?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Florence to Boston?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Florence to Boston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

07-23

COP 365,706

07-24

COP 339,490

Today

COP 423,157

07-26

COP 528,150

07-27

COP 305,039

07-28

COP 362,458

07-29

No data

07-30

COP 444,484

The cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Jul 27, 2026 with a price of COP 305,039

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US, as early as possible.

You can expect to pay from COP 305,039 to COP 529,758 for a bus ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at COP 305,039 which is on 2026-07-27.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.