Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus station | Harrisburg Bus Station | CheapestFastest |
Last refresh of the prices: Yesterday at 6:21 AM EST.
Compare 2 ways to travel from Florence to Harrisburg
Among the sustainable travel choices, the train stands out as a good way to reach Harrisburg. The journey takes about 13 hours 15 minutes and with fares starting at just R 3 027, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Harrisburg?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
Compare bus companies
Frequently asked questions about travelling from Florence, SC, US to Harrisburg by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Florence to Harrisburg?
The cheapest bus tickets from Florence to Harrisburg start at R 2 066. The average price for this route is around R 2 839. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Florence to Harrisburg?
The average bus journey time from Florence to Harrisburg is 21h 25m, covering a distance of 722 km. The fastest bus gets you there in 21h 25m and is operated by Greyhound.
Which bus companies service the Florence to Harrisburg route?
What is the earliest and latest departure time for the bus from Florence to Harrisburg?
The earliest bus departs from Florence to Harrisburg at 00:05. And the latest bus departs at 16:30.
What are the CO₂ emissions for the bus trip from Florence to Harrisburg?
A bus trip from Florence to Harrisburg produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Florence to Harrisburg?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Florence to Harrisburg?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Florence to Harrisburg?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Harrisburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Harrisburg was searched and found on 01 Jan 2026 with a price of R 2 700To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Harrisburg as early as possible.
What's the cheapest way to go from Florence, SC, US to Harrisburg?
The bus is the cheapest travel choice for this destination
