Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 1116 Woodruff Rd | Columbus (E Mound St) | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Columbus (E Mound St) | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | 100 E Rich St | No tags |
Last refresh of the prices: Yesterday at 4:33 PM EST.
Get from Greenville to Columbus
The journey takes about 17 hours, and with fares starting at just R 2 131, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Columbus?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Columbus
- A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
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Frequently asked questions about travelling from Greenville, SC to Columbus, OH by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Greenville to Columbus?
The cheapest bus tickets from Greenville to Columbus start at R 2 131. The average price for this route is around R 2 980. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Greenville to Columbus?
The average bus journey time from Greenville to Columbus is 17h, covering a distance of 574 km. The fastest bus gets you there in 17h and is operated by Greyhound.
Which bus companies service the Greenville to Columbus route?
What is the earliest and latest departure time for the bus from Greenville to Columbus?
The earliest bus departs from Greenville to Columbus at 14:45. And the latest bus departs at 22:00.
What are the CO₂ emissions for the bus trip from Greenville to Columbus?
A bus trip from Greenville to Columbus produces an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Greenville to Columbus?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Greenville to Columbus?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Greenville to Columbus?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Columbus?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Columbus, OH was searched and found on 06 Jan 2026 with a price of R 1 867To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Columbus, OH as early as possible.
You can expect to pay from R 1 867 to R 3 011 for a bus ticket from Greenville, SC to Columbus, OH based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 867, which is on 2026-01-06.
