Cheap buses leaving Sunday
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
- Departure time: July 20 atDeparture city: GreenvilleDeparture location: 1116 Woodruff RdArrival time: July 21 atDestination city: ColumbusDestination location: Columbus (E Mound St)Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Last Sunday at 7:44 PM EDT.
Prices and availability are subject to change.
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Bus Greenville to Columbus: Trip Overview
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Greenville to Columbus Bus
Busbud helps you find a bus from Greenville to Columbus. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Greenville to Columbus.
Whether it is cheap bus tickets or more luxurious buses going to Columbus from Greenville, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Greenville and Columbus?
Frequently asked questions on the trip Greenville, SC - Columbus, OH
What is the travel distance from Greenville to Columbus?
It's about 572 km (355 miles) from Greenville to Columbus.
What are the departure and arrival locations for buses traveling from Greenville to Columbus?
Buses departing from Guadalajara Supermarket Bus Stop in Greenville will take you to Columbus Bus Station in Columbus.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville to Columbus was searched and found on Jul 17, 2025 with a price of US$112To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Columbus, as early as possible.
You can expect to pay from US$112 to US$160 for a bus ticket from Greenville to Columbus based on the last 2 days. You can expect to find the cheapest price for the trip at US$160 which is on 2025-07-20.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Columbus!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Greenville to Columbus.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Greenville to Columbus.
Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Columbus while indulging in miles on end of beautiful scenic views.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
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