Find coaches from Greenville, SC to Columbus, OH

Find affordable coach tickets from Greenville, SC to Columbus, OH with flexible options. Book your journey now

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Today16 Jul
from US$119
Tomorrow17 Jul
from US$120
Fri18 Jul
Sat19 Jul
Sun20 Jul
from US$123
Mon21 Jul
Tue22 Jul
Wed23 Jul

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 17 July at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 18 July at
    Destination city: Columbus
    Destination location: Columbus (E Mound St)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 17 July at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 18 July at
    Destination city: Columbus
    Destination location: Columbus (E Mound St)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 17 July at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 18 July at
    Destination city: Columbus
    Destination location: 100 E Rich St
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 17 July at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 18 July at
    Destination city: Columbus
    Destination location: 100 E Rich St
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 17 July at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 18 July at
    Destination city: Columbus
    Destination location: Columbus (E Mound St)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Greenville to Columbus: Trip Overview

Average ticket priceUS$121
Average bus trip duration17h
Number of daily buses4
Earliest bus departure14:45
Distance356 miles
Latest bus departure22:00

Greenville to Columbus Bus

Busbud helps you find a bus from Greenville to Columbus. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Greenville to Columbus.

Whether it is cheap bus tickets or more luxurious buses going to Columbus from Greenville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Greenville, SC - Columbus, OH

  1. How far is Columbus from Greenville by coach?

    The journey from Greenville to Columbus by coach covers an approximate distance of 355 miles (572 km).

  2. Is there a way to reach Columbus from Greenville without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
14/07
No data
15/07
No data
Today
US$115
17/07
US$112
18/07
No data
19/07
No data
20/07
US$160
21/07
No data
busbud logoThe cheapest trip from Greenville to Columbus was searched and found on 17 Jul 2025 with a price of US$112

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Columbus as early as possible.

You can expect to pay from US$112 to US$160 for a bus ticket from Greenville to Columbus based on the last 2 days. You can expect to find the cheapest price for the trip at US$112, which is on 2025-07-17.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Columbus!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Greenville to Columbus.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Greenville to Columbus.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Columbus while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Greenville by bus?

Bus from Greenville to Columbus

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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