Find coaches from Greenville, SC to Jacksonville, FL

Previously seen journeys

Next departures from Greenville to Jacksonville on 15 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Bus
1116 Woodruff Rd
Jacksonville Bus StationNo tags
FlixBusBus
1116 Woodruff Rd
Jacksonville Bus StationNo tags
GreyhoundBus
1116 Woodruff Rd
Jacksonville Bus StationNo tags
FlixBus + Greyhound
Bus
1116 Woodruff Rd
Jacksonville Bus StationNo tags
FlixBus + Greyhound
Bus
1116 Woodruff Rd
Jacksonville Bus StationNo tags

Compare 2 ways to travel from Greenville to Jacksonville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Jacksonville. The journey takes about 11 hours 40 minutes and with fares starting at just R 1 194, it presents an excellent value for a comfortable ride.

2bus per day
11h 40mAverage duration
504 kmDistance
13kgCO₂ emissions
Bus
Average priceR 1 194 - R 3 023Average duration11h 40m
13kg CO₂e
Train
Average priceR 2 758 - R 36 740Average duration1d 4h
46kg CO₂e

Frequently asked questions about travelling from Greenville, SC to Jacksonville, FL by bus

  1. How much does a bus ticket from Greenville to Jacksonville cost?

    The bus ticket price from Greenville to Jacksonville starts at R 1 194. The best way to find cheap bus tickets from Greenville to Jacksonville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Greenville to Jacksonville?

    The average travel time between Greenville and Jacksonville is around 11h 40m, although the fastest bus will take about 11h 15m. This is the time it takes to travel the 508 km that separates the two cities.

  3. How many daily bus connections are there between Greenville and Jacksonville?

    The number of buses from Greenville to Jacksonville can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Greenville to Jacksonville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Greenville to Jacksonville?

    When taking the bus from Greenville to Jacksonville, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Greenville to Jacksonville?

    Buses travelling between Greenville and Jacksonville leave from Guadalajara Supermarket Bus Stop or Greenville Bus Station and arrive at Jacksonville Amtrak Station, W Forsyth St, Kings Avenue Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
13/11
No data
14/11
R 2 057
Today
No data
16/11
No data
17/11
No data
18/11
No data
19/11
No data
20/11
No data
busbud logoThe cheapest trip from Greenville, SC to Jacksonville, FL was searched and found on 14 Nov 2025 with a price of R 2 057

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Jacksonville, FL as early as possible.

What's the cheapest way to go from Greenville, SC to Jacksonville, FL?

busbud logoThe bus is the cheapest travel choice for this destination

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