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Compare 2 ways to go from Greenville to Jacksonville.
Busbud recommends taking the bus from Greenville to JacksonvilleAmong the sustainable travel choices, the bus stands out as the good way to reach Jacksonville. The journey takes about 15 hours 35 minutes and with fares starting at just $65, it presents an excellent value for a comfortable ride.
Bus Greenville, SC to Jacksonville, FL: Trip Overview
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Greenville to Jacksonville Bus
Busbud helps you find a bus from Greenville to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Greenville to Jacksonville.
Discover how much the bus trip from Greenville to Jacksonville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Greenville and Jacksonville?
Frequently asked questions for your trip Greenville, SC - Jacksonville, FL
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Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Jacksonville, FL was searched and found on Aug 27, 2025 with a price of $69To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Jacksonville, FL, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Jacksonville!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Greenville to Jacksonville.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Jacksonville will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Jacksonville.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
What's the cheapest way to go from Greenville, SC to Jacksonville, FL?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Charleston
- Bus Greenville - Spartanburg
- Greenville - Charleston
- Bus from Greenville to Greensboro
- Bus Greenville - Chicago
- Greenville - Miami
- Bus from Greenville to Atlanta
- Bus Greenville - Charlotte
- Greenville - New York City
- Bus from Greenville to Knoxville
- Bus Greenville - Tarboro
- Greenville - Anderson
- Bus from Greenville to Macon
- Bus Greenville - Orlando
- Greenville - Dallas
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Bus Burlington - Greenville
- Nashville - Greenville
- Bus from Knoxville to Greenville
- Bus Savannah - Greenville
- Orlando - Greenville
- Bus from Charlotte to Greenville
- Bus Charleston - Greenville
- Anderson - Greenville
- Bus from Asheville to Greenville
- Bus New York City - Greenville
- LaGrange - Greenville
- Bus from Miami to Greenville
- Bus Fayetteville - Greenville
- Spartanburg - Greenville
Popular Buses Connecting Jacksonville
Buses Leaving from Jacksonville
- Bus from Jacksonville to Jacksonville
- Bus Jacksonville - Miami
- Jacksonville - Atlanta
- Bus from Jacksonville to Savannah
- Bus Jacksonville - Gainesville
- Jacksonville - Gainesville
- Bus from Jacksonville to Orlando
- Bus Jacksonville - Tallahassee
- Jacksonville - Tampa
- Bus from Jacksonville to New York City
- Bus Jacksonville - Fort Lauderdale
- Jacksonville - Ocala
- Bus from Jacksonville to West Palm Beach
- Bus Jacksonville - Houston
- Jacksonville - Daytona Beach
Buses Going to Jacksonville
- Bus from Jacksonville to Jacksonville
- Bus Orlando - Jacksonville
- Tampa - Jacksonville
- Bus from Miami to Jacksonville
- Bus San Marcos - Jacksonville
- Charlotte - Jacksonville
- Bus from Atlanta to Jacksonville
- Bus Gainesville - Jacksonville
- Tallahassee - Jacksonville
- Bus from Fort Lauderdale to Jacksonville
- Bus New York City - Jacksonville
- Ocala - Jacksonville
- Bus from Fort Myers to Jacksonville
- Bus Daytona Beach - Jacksonville
- Charleston - Jacksonville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Miami - Tampa
- Bus from Seattle to Leavenworth
- Bus Austin - Dallas
- Dallas - Austin
- Bus from Houston to San Antonio
- Bus Austin - Houston
- Orlando - Atlanta
- Bus from New York City to Los Angeles
- Bus Dallas - San Antonio
- Houston - Austin