Find coaches from Indianapolis to San Ysidro, CA

Next departures

Next departures from Indianapolis to San Ysidro on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Indianapolis Bus Station
San Ysidro Bus terminalCheapest
Greyhound Lines, Inc.
Indianapolis Bus Station
San Ysidro Bus terminalFastest
Greyhound Lines, Inc. + FlixBus
Indianapolis Bus Station
San Ysidro Greyhound Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Indianapolis Bus Station
San Ysidro Greyhound Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
San Ysidro Bus terminalNo tags

Last refresh of the prices: Last Wednesday at 2:51 PM EDT.

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Get from Indianapolis to San Ysidro

busbud logoThis route is served by bus only

The journey takes about 2 days, 14 hours 5 minutes, and with fares starting at just US$171, it presents an excellent value for a comfortable ride.

8bus per day
2d 14hAverage duration
2871 kmDistance
72kgCO₂ emissions

Bus Indianapolis to San Ysidro, CA: Trip Overview

Average ticket priceUS$280
Average bus trip duration2d 14h
Number of daily buses8
Earliest bus departure03:15
Distance2870 km
Latest bus departure23:30

Indianapolis to San Ysidro Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Indianapolis to San Ysidro.

Bus service from Indianapolis to San Ysidro will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Indianapolis to San Ysidro, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Indianapolis - San Ysidro, CA

  1. How much does a bus ticket from Indianapolis to San Ysidro cost?

    The bus ticket price from Indianapolis to San Ysidro starts at US$171. The best way to find cheap bus tickets from Indianapolis to San Ysidro is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Indianapolis to San Ysidro?

    The average travel time between Indianapolis and San Ysidro is around 2d 14h, although the fastest bus will take about 2d . This is the time it takes to travel the 2874 km that separates the two cities.

  3. How many daily bus connections are there between Indianapolis and San Ysidro?

    The number of buses from Indianapolis to San Ysidro can differ depending on the day of the week. On average, there are 8 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Indianapolis to San Ysidro by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Indianapolis to San Ysidro?

    When taking the bus from Indianapolis to San Ysidro, you can travel comfortably and safely with Greyhound.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/10
US$476
30/10
US$343
Today
US$287
01/11
No data
02/11
US$298
03/11
No data
04/11
No data
05/11
No data
busbud logoThe cheapest trip from Indianapolis to San Ysidro, CA was searched and found on 31 Oct 2025 with a price of US$287

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to San Ysidro, CA as early as possible.

You can expect to pay from US$287 to US$476 for a bus ticket from Indianapolis to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at US$298, which is on 2025-11-02.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Indianapolis to San Ysidro but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Indianapolis to San Ysidro, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Indianapolis to San Ysidro that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to San Ysidro while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Indianapolis by bus?

Bus from San Ysidro, CA to Indianapolis

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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