Bus Tickets from Indianapolis to San Ysidro, CA

Next departures

Next departures for Indianapolis to San Ysidro on November 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
    		Indianapolis Northeast
    		San Ysidro Bus terminalCheapest
    Greyhound Lines, Inc.
      		Indianapolis Bus Station
      		San Ysidro Bus terminalFastest
      Greyhound Lines, Inc. + FlixBus
        		Indianapolis Bus Station
        		San Ysidro Bus terminalNo tags
        FlixBus + Greyhound Lines, Inc.
          		Downtown Transit Center
          		San Ysidro Bus terminalNo tags
          FlixBus + Greyhound Lines, Inc.
            		Downtown Transit Center
            		San Ysidro Bus terminalNo tags

            Last refresh of the prices: Last Wednesday at 2:51 PM EDT.

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            Get from Indianapolis to San Ysidro

            busbud logoThis route is served by bus only

            The journey takes about 2 days, 14 hours 5 minutes and with fares starting at just $171, it presents an excellent value for a comfortable ride.

            8bus per day
            2d 14hAverage Duration
            1780 milesDistance
            72kgCO₂ emissions

            Bus Indianapolis to San Ysidro, CA: Trip Overview

            Average ticket price$280
            Average bus trip duration2d 14h
            Number of daily buses8
            Earliest bus departure3:15am
            Distance1780 miles (2870 km)
            Latest bus departure11:30pm

            Indianapolis to San Ysidro Bus

            Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Indianapolis to San Ysidro.

            Bus service from Indianapolis to San Ysidro will be provided by the most trusted bus companies.

            From cheap bus tickets to more luxurious buses traveling from Indianapolis to San Ysidro, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions for your trip Indianapolis - San Ysidro, CA

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            10/29
            $476
            10/30
            $343
            Today
            $287
            11/01
            No data
            11/02
            $278
            11/03
            No data
            11/04
            No data
            11/05
            No data
            busbud logoThe cheapest trip from Indianapolis to San Ysidro, CA was searched and found on Nov 2, 2025 with a price of $278

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to San Ysidro, CA, as early as possible.

            You can expect to pay from $278 to $476 for a bus ticket from Indianapolis to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $278 which is on 2025-11-02.

            About Bus Travel

            Bus Travel Tips

            If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Indianapolis to San Ysidro but it'll also be endearing to native speakers who will surely appreciate your effort.

            Much more than a mere vehicle taking you from Indianapolis to San Ysidro, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Indianapolis to San Ysidro that are otherwise impossible to come by with a plane.

            Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to San Ysidro while indulging in miles on end of beautiful scenic views.

            Did you know?

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

            The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

            Will you be returning to Indianapolis by bus?

            Bus from San Ysidro, CA to Indianapolis

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            Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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