Find coaches from Itajaí to Santa Maria, RS, BR

Previously seen journeys

Next departures from Itajaí to Santa Maria on 3 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
União Santa Cruz
    		Terminal Rodoviário Internacional de Itajaí
    		Terminal Rodoviário de Santa MariaNo tags
    União Santa Cruz
      		Terminal Rodoviário Internacional de Itajaí
      		Terminal Rodoviário de Santa MariaNo tags
      União Santa Cruz
        		Itajaí Bus Terminal
        		Terminal Rodoviário de Santa MariaNo tags
        União Santa Cruz
          		Itajaí Bus Terminal
          		Terminal Rodoviário de Santa MariaNo tags
          União Santa Cruz
            		Itajaí Bus Terminal
            		Terminal Rodoviário de Santa MariaNo tags

            Accepted payments

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            Get from Itajaí to Santa Maria

            This route is served by bus only

            The journey takes about 13 hours 45 minutes, and with fares starting at just US$56, it presents an excellent value for a comfortable ride.

            2bus per day
            13h 45mAverage duration
            588 kmDistance
            15kgCO₂ emissions

            Bus Itajaí to Santa Maria, RS, BR: Trip Overview

            Average ticket priceUS$79
            Average bus trip duration13h 45m
            Number of daily buses2
            Earliest bus departure07:15
            Distance587 km
            Latest bus departure20:00

            Itajaí to Santa Maria Bus

            Busbud helps you find a bus from Itajaí to Santa Maria. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

            Bus service from Itajaí to Santa Maria will be provided by the most trusted bus companies.

            Whether it is cheap bus tickets or more luxurious buses going to Santa Maria from Itajaí, we help you find what you're looking for based on how much of a budget you have.

            Frequently asked questions on the trip Itajaí - Santa Maria, RS, BR

            1. How much does a bus ticket from Itajaí to Santa Maria cost?

              The bus ticket price from Itajaí to Santa Maria starts at US$56. The best way to find cheap bus tickets from Itajaí to Santa Maria is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Itajaí to Santa Maria?

              The average travel time between Itajaí and Santa Maria is around 13h 45m, although the fastest bus will take about 12h 55m. This is the time it takes to travel the 593 km that separates the two cities.

            3. How many daily bus connections are there between Itajaí and Santa Maria?

              The number of buses from Itajaí to Santa Maria can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Itajaí to Santa Maria by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Itajaí to Santa Maria?

              When taking the bus from Itajaí to Santa Maria, you can travel comfortably and safely with União Santa Cruz.

            5. What are the departure and arrival stations when taking the bus from Itajaí to Santa Maria?

              Buses travelling between Itajaí and Santa Maria leave from Itajaí Bus Terminal or Terminal Rodoviário Internacional de Itajaí and arrive at Terminal Rodoviário de Santa Maria.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            31/10
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            01/11
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            Today
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            03/11
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            06/11
            US$49
            07/11
            No data
            busbud logoThe cheapest trip from Itajaí to Santa Maria, RS, BR was searched and found on 06 Nov 2025 with a price of US$49

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Itajaí to Santa Maria, RS, BR as early as possible.

            You can expect to pay from US$49 to US$68 for a bus ticket from Itajaí to Santa Maria, RS, BR based on the last 2 days. You can expect to find the cheapest price for the trip at US$49, which is on 2025-11-06.

            About Bus Travel

            Bus Travel Tips

            Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Itajaí and Santa Maria!

            Much more than a mere vehicle taking you from Itajaí to Santa Maria, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Itajaí to Santa Maria.

            Tune out to the fine sounds of your best music playlist on your bus trip from Itajaí to Santa Maria while indulging in miles on end of beautiful scenic views.

            Did you know?

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

            Will you be returning to Itajaí by bus?

            Bus from Santa Maria, RS, BR to Itajaí

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