Bus Tickets from Itajaí to Santa Maria

Find affordable bus tickets from Itajaí to Santa Maria with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 16
from $46
TomorrowMay 17
SunMay 18
MonMay 19
TueMay 20
WedMay 21
ThuMay 22
FriMay 23

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 16 at
    Departure city: Itajaí
    Departure location: Itajaí Bus Terminal
    Arrival time: May 17 at
    Destination city: Santa Maria
    Destination location: Terminal Rodoviário de Santa Maria
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 16 at
    Departure city: Itajaí
    Departure location: Itajaí Bus Terminal
    Arrival time: May 17 at
    Destination city: Santa Maria
    Destination location: Terminal Rodoviário de Santa Maria
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • Departure time: May 16 at
    Departure city: Itajaí
    Departure location: Itajaí Bus Terminal
    Arrival time: May 17 at
    Destination city: Santa Maria
    Destination location: Terminal Rodoviário de Santa Maria
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • Departure time: May 16 at
    Departure city: Itajaí
    Departure location: Itajaí Bus Terminal
    Arrival time: May 17 at
    Destination city: Santa Maria
    Destination location: Terminal Rodoviário de Santa Maria
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • Departure time: May 16 at
    Departure city: Itajaí
    Departure location: Itajaí Bus Terminal
    Arrival time: May 17 at
    Destination city: Santa Maria
    Destination location: Terminal Rodoviário de Santa Maria
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Itajaí to Santa Maria: Trip Overview

Average ticket price$75
Average bus trip duration13h 45m
Number of daily buses2
Earliest bus departure7:15am
Distance364 miles (587 km)
Latest bus departure8:00pm

Itajaí to Santa Maria Bus

Busbud helps you find a bus from Itajaí to Santa Maria. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Itajaí to Santa Maria will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Santa Maria from Itajaí, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Itajaí - Santa Maria

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/14
No data
05/15
$46
Today
$46
05/17
$46
05/18
$48
05/19
$46
05/20
No data
05/21
$46
busbud logoThe cheapest trip from Itajaí to Santa Maria was searched and found on May 21, 2025 with a price of $46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Itajaí to Santa Maria, as early as possible.

You can expect to pay from $46 to $65 for a bus ticket from Itajaí to Santa Maria based on the last 2 days. You can expect to find the cheapest price for the trip at $46 which is on 2025-05-21.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Itajaí and Santa Maria!

Much more than a mere vehicle taking you from Itajaí to Santa Maria, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Itajaí to Santa Maria.

Tune out to the fine sounds of your best music playlist on your bus trip from Itajaí to Santa Maria while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Itajaí by bus?

Bus from Itajaí to Santa Maria

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Itajaí

Buses Leaving from Itajaí

Buses Going to Itajaí

Popular Buses Connecting Santa Maria

Buses Leaving from Santa Maria

Buses Going to Santa Maria