Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Itajaí Bus Terminal | Terminal Rodoviário de Santa Maria | No tags | ||||
| Bus | Itajaí Bus Terminal | Terminal Rodoviário de Santa Maria | No tags | ||||
| Bus | Itajaí Bus Terminal | Terminal Rodoviário de Santa Maria | No tags | ||||
| Bus | Itajaí Bus Terminal | Terminal Rodoviário de Santa Maria | No tags | ||||
| Bus | Terminal Rodoviário Internacional de Itajaí | Terminal Rodoviário de Santa Maria | No tags |
Get from Itajaí to Santa Maria
The journey takes about 13 hours 45 minutes and with fares starting at just $57, it presents an excellent value for a comfortable ride.
Where are the popular stops in Itajaí and Santa Maria?
Stops in Itajaí
- AAv. Gov. Adolfo Konder, 1583-1705 - Cidade Nova, Itajaí - SC, Brazil
- B
Terminal Rodoviário Internacional de Itajaí
Avenida Governador Adolfo Konder, 1201 - São Vicente, Itajaí - SC 88308-000 - C
Vila Operaria - Itajai
Vila Operária, Rio de Janiero, Brasil
Stops in Santa Maria
- A
Terminal Rodoviário de Santa Maria
Rua Pedro Pereira 1450 - lj 101, Santa Maria - RS, 72547-700
Compare bus companies
Based on 16 reviews, the company was rated 4.5 stars on Busbud. Travelers were especially satisfied with the staff and the seats but often complained with the wifi. União Santa Cruz ticket prices on this trip start at $57
Frequently asked questions about traveling from Itajaí to Santa Maria, RS, BR by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Itajaí to Santa Maria?
The cheapest bus tickets from Itajaí to Santa Maria start from $57. The average price for this route is around $80. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Itajaí to Santa Maria?
The average bus trip duration from Itajaí to Santa Maria is 13h 45m, covering a distance of 365 miles (588 km). The quickest bus can get you there in 12h 55m and is operated by União Santa Cruz.
Which bus companies service the Itajaí to Santa Maria route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Itajaí to Santa Maria?
The earliest bus departs from Itajaí to Santa Maria at 7:15am. And the latest bus departs at 8:00pm.
What are the CO₂ emissions for the bus trip from Itajaí to Santa Maria?
A bus trip from Itajaí to Santa Maria generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Itajaí to Santa Maria, RS, BR was searched and found on Nov 25, 2025 with a price of $49To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Itajaí to Santa Maria, RS, BR, as early as possible.
You can expect to pay from $49 to $82 for a bus ticket from Itajaí to Santa Maria, RS, BR based on the last 2 days. You can expect to find the cheapest price for the trip at $49 which is on 2025-11-28.
