Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Andimar + Flixbus Chile | Bus | La Serena (Bus terminal La Serena) | Talca (Cruce Varoli) | CheapestFastest | ||||
Andimar + Flixbus Chile | Bus | La Serena (Bus terminal La Serena) | Talca (Cruce Varoli) | No tags | ||||
 | Bus | La Serena (Bus terminal La Serena) | Talca (Cruce Varoli) | No tags |
Last refresh of the prices: Today at 12:28 AM -03.
Get from La Serena to Talca
The journey takes about 10 hours 50 minutes, and with fares starting at just R 350, it presents an excellent value for a comfortable ride.
Where are the popular stops in La Serena and Talca?
Stops in La Serena
- AAmunátegui 107, La Serena, Región de Coquimbo, Chile
- B
Rotonda La Serena
Panamericana Norte 208, La Serena, Región de Coquimbo, Chile
Stops in Talca
- ADos Sur / Doce y Trece Oriente, Talca, VII Región, Chile
- B
Parada de Autobus Talca Varoli
Rho 1131, Talca, VII Región, Chile - C
Parada de Autobus Talca Cruce Varoli
Veintiuno Ote 253, Talca, VII Región, Chile - D
Estación de Ferrocarriles de Talca
Once Ote 900-1002, Talca, VII Región, Chile - E
Terminal Tur Bus de Talca
Trece Ote 851-889, Talca, VII Región, Chile - F
Cruce Sur San Javier
Sgto Aldea 2456, San Javier, VII Región, Chile
Compare bus companies
Based on 12162 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. FlixBus ticket prices on this trip start at R 350
Frequently asked questions about travelling from La Serena, CL to Talca by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from La Serena to Talca?
The cheapest bus tickets from La Serena to Talca start at R 350. The average price for this route is around R 556. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from La Serena to Talca?
The average bus journey time from La Serena to Talca is 10h 50m, covering a distance of 617 km. The fastest bus gets you there in 10h 10m and is operated by FlixBus.
Which bus companies service the La Serena to Talca route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from La Serena to Talca?
The earliest bus departs from La Serena to Talca at 02:20. And the latest bus departs at 23:50.
What are the CO₂ emissions for the bus trip from La Serena to Talca?
A bus trip from La Serena to Talca produces an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from La Serena, CL to Talca was searched and found on 28 Jan 2026 with a price of R 359To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Talca as early as possible.
You can expect to pay from R 359 to R 662 for a bus ticket from La Serena, CL to Talca based on the last 2 days. You can expect to find the cheapest price for the trip at R 607, which is on 2026-02-02.
