Find coaches from La Serena, CL to Antofagasta

Next departures

Next departures from La Serena to Antofagasta on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Cikbus Elité
Terminal de Buses La Serena
Terminal AntofagastaCheapest
Cikbus Elité
Terminal de Buses La Serena
Terminal AntofagastaFastest
Cikbus Elité
Terminal de Buses La Serena
Terminal AntofagastaNo tags
Pluss Chile
Terminal de Buses La Serena
Terminal AntofagastaNo tags
Pullman San Andrés
Terminal de Buses La Serena
Terminal Carlos Oviedo CavadaNo tags

Last refresh of the prices: Today at 6:08 PM -03.

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Get from La Serena to Antofagasta

busbud logoThis route is served by bus only

The journey takes about 11 hours 35 minutes, and with fares starting at just US$21, it presents an excellent value for a comfortable ride.

30bus per day
11h 35mAverage duration
705 kmDistance
18kgCO₂ emissions

Bus La Serena, CL to Antofagasta: Trip Overview

Average ticket priceUS$41
Average bus trip duration11h 35m
Number of daily buses30
Earliest bus departure00:05
Distance705 km
Latest bus departure23:59

La Serena to Antofagasta Bus

Busbud helps you find a bus from La Serena to Antofagasta. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from La Serena to Antofagasta will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Antofagasta from La Serena, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip La Serena, CL - Antofagasta

  1. How much does a bus ticket from La Serena to Antofagasta cost?

    The bus ticket price from La Serena to Antofagasta starts at US$21. The best way to find cheap bus tickets from La Serena to Antofagasta is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from La Serena to Antofagasta?

    The average travel time between La Serena and Antofagasta is around 11h 35m, although the fastest bus will take about 10h 40m. This is the time it takes to travel the 704 km that separates the two cities.

  3. How many daily bus connections are there between La Serena and Antofagasta?

    The number of buses from La Serena to Antofagasta can differ depending on the day of the week. On average, there are 30 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from La Serena to Antofagasta by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from La Serena to Antofagasta?

    When taking the bus from La Serena to Antofagasta, you can travel comfortably and safely with Pluss Chile, Pullman San Andres, Cikbus Elité.

  5. What are the departure and arrival stations when taking the bus from La Serena to Antofagasta?

    Buses travelling between La Serena and Antofagasta leave from Terminal de Buses La Serena or Rotonda La Serena and arrive at Terminal Antofagasta, Av. Pedro Aguirre Cerda, 253, Terminal Flota Barrios.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$29
29/10
US$28
Today
US$27
31/10
US$20
01/11
US$27
02/11
US$27
03/11
US$27
04/11
US$27
busbud logoThe cheapest trip from La Serena, CL to Antofagasta was searched and found on 31 Oct 2025 with a price of US$20

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Antofagasta as early as possible.

You can expect to pay from US$20 to US$53 for a bus ticket from La Serena, CL to Antofagasta based on the last 2 days. You can expect to find the cheapest price for the trip at US$20, which is on 2025-10-31.

Usually Pluss Chile, Pullman San Andres will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between La Serena and Antofagasta!

Much more than a mere vehicle taking you from La Serena to Antofagasta, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from La Serena to Antofagasta.

Make a music playlist for your bus ride from La Serena to Antofagasta, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to La Serena, CL by bus?

Bus from Antofagasta to La Serena, CL

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