Find coaches from Myrtle Beach to San Diego, CA, US

Previously seen journeys

Next departures from Myrtle Beach to San Diego on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
    		Bus Station
    		Downtown SD (Seaport)No tags
    FlixBus + Greyhound
      		Bus Station
      		Balboa ParkNo tags
      Greyhound + FlixBus
        		Bus Station
        		San Diego (Old Town-FlixBus)No tags
        Greyhound
          		Bus Station
          		Greyhound Bus StopNo tags
          Greyhound + FlixBus
            		Bus Station
            		UCSD Health La Jolla StationNo tags

            Accepted payments

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            Get from Myrtle Beach to San Diego

            This route is served by bus only

            The journey takes about 3 days, 3 hours 55 minutes, and with fares starting at just US$338, it presents an excellent value for a comfortable ride.

            4bus per day
            3d 3hAverage duration
            3544 kmDistance
            89kgCO₂ emissions

            Bus Myrtle Beach to San Diego, CA, US: Trip Overview

            Average ticket priceUS$338
            Average bus trip duration3d 3h
            Number of daily buses4
            Earliest bus departure12:45
            Distance3544 km

            Myrtle Beach to San Diego Bus

            With Busbud, comparing and booking tickets for a bus from Myrtle Beach to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make sure you can find a bus service from Myrtle Beach to San Diego from the most reliable bus companies operating this trip.

            Discover how much the bus trip from Myrtle Beach to San Diego will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

            Frequently asked questions on the trip Myrtle Beach - San Diego, CA, US

            1. How much does a bus ticket from Myrtle Beach to San Diego cost?

              The bus ticket price from Myrtle Beach to San Diego starts at US$338. The best way to find cheap bus tickets from Myrtle Beach to San Diego is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Myrtle Beach to San Diego?

              The average travel time between Myrtle Beach and San Diego is around 3d 3h, although the fastest bus will take about 3d 2h. This is the time it takes to travel the 3546 km that separates the two cities.

            3. How many daily bus connections are there between Myrtle Beach and San Diego?

              The number of buses from Myrtle Beach to San Diego can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Myrtle Beach to San Diego by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Myrtle Beach to San Diego?

              When taking the bus from Myrtle Beach to San Diego, you can travel comfortably and safely with Greyhound.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            31/10
            No data
            01/11
            US$344
            Today
            No data
            03/11
            No data
            04/11
            No data
            05/11
            No data
            06/11
            No data
            07/11
            No data
            busbud logoThe cheapest trip from Myrtle Beach to San Diego, CA, US was searched and found on 01 Nov 2025 with a price of US$344

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to San Diego, CA, US as early as possible.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while travelling from Myrtle Beach to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from Myrtle Beach to San Diego, get comfy and count the stars.

            Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Myrtle Beach to San Diego will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Myrtle Beach to San Diego.

            Did you know?

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

            Will you be returning to Myrtle Beach by bus?

            Bus from San Diego, CA, US to Myrtle Beach

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