Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Bus Station | Downtown SD (Seaport) | No tags | ||||
FlixBus + Greyhound | Bus | Bus Station | Balboa Park | No tags | ||||
Greyhound + FlixBus | Bus | Bus Station | San Diego (Old Town-FlixBus) | No tags | ||||
 | Bus | Bus Station | Greyhound Bus Stop | No tags | ||||
Greyhound + FlixBus | Bus | Bus Station | UCSD Health La Jolla Station | No tags |
Get from Myrtle Beach to San Diego
The journey takes about 3 days, 20 minutes, and with fares starting at just R 7 178, it presents an excellent value for a comfortable ride.
Where are the popular stops in Myrtle Beach and San Diego?
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Based on 87439 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 7 178
Frequently asked questions about travelling from Myrtle Beach to San Diego, CA, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Myrtle Beach to San Diego?
The cheapest bus tickets from Myrtle Beach to San Diego start at R 7 178. The average price for this route is around R 7 230. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Myrtle Beach to San Diego?
The average bus journey time from Myrtle Beach to San Diego is 3d , covering a distance of 3544 km. The fastest bus gets you there in 3d 2h and is operated by Greyhound.
Which bus companies service the Myrtle Beach to San Diego route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Myrtle Beach to San Diego?
The earliest bus departs from Myrtle Beach to San Diego at 12:45. And the latest bus departs at 12:45.
What are the CO₂ emissions for the bus trip from Myrtle Beach to San Diego?
A bus trip from Myrtle Beach to San Diego produces an estimated 89 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Myrtle Beach to San Diego, CA, US was searched and found on 17 Dec 2025 with a price of R 10 343To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to San Diego, CA, US as early as possible.
