- Myrtle Beach to San Diego buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Bus Station | Downtown SD (Seaport) | No tags | ||||
FlixBus + Greyhound | Bus | Bus Station | Balboa Park | No tags | ||||
Greyhound + FlixBus | Bus | Bus Station | San Diego (Old Town-FlixBus) | No tags | ||||
![]() | Bus | Bus Station | Greyhound Bus Stop | No tags | ||||
Greyhound + FlixBus | Bus | Bus Station | UCSD Health La Jolla Station | No tags |
Get from Myrtle Beach to San Diego
This route is served by bus only
The journey takes about 3 days, 3 hours, and with fares starting at just $506, it presents an excellent value for a comfortable ride.
3bus per day
3d 3hAverage Duration
3544 kmDistance
89kgCO₂ emissions
Where are the popular stops in Myrtle Beach and San Diego?
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
3.5 out of 5 stars3.5/587,396 reviews
Based on 87396 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $506
US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about travelling from Myrtle Beach to San Diego, CA, US by bus
How far is Myrtle Beach from San Diego?
The distance covered from Myrtle Beach to San Diego is 3546 km (2199 miles).
What are the departure and arrival locations for buses traveling from Myrtle Beach to San Diego?
Buses traveling this route start their trip at Bus Station, in Myrtle Beach, and end it at Mission Valley Sheraton, in San Diego.






