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One passenger / one way
- This trip is recommended because it is: Cheapest
- This trip is recommended because it is: Fastest
- Departure time: July 28 atDeparture city: Myrtle BeachDeparture location: Bus StationArrival time: July 31 atDestination city: San DiegoDestination location: Greyhound Bus StopOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
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Bus Myrtle Beach to San Diego, CA, US: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Myrtle Beach to San Diego Bus
With Busbud, comparing and booking tickets for a bus from Myrtle Beach to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
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Discover how much the bus trip from Myrtle Beach to San Diego will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Myrtle Beach and San Diego?
Frequently asked questions for your trip Myrtle Beach - San Diego, CA, US
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Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Myrtle Beach to San Diego, CA, US was searched and found on Jul 28, 2025 with a price of $489To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to San Diego, CA, US, as early as possible.
You can expect to pay from $489 to $489 for a bus ticket from Myrtle Beach to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $489 which is on 2025-07-28.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Myrtle Beach to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Myrtle Beach to San Diego, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Myrtle Beach to San Diego will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Myrtle Beach to San Diego.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top traveled bus routes
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular bus departures from Myrtle Beach
Popular bus departures to Myrtle Beach
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