Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Gateway Station | Cheapest | ||||
 | Bus | Orlando Bus Station | Gateway Station | Fastest | ||||
 | Bus | Orlando Bus Station | Gateway Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | The Florida Mall | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 12:24 AM EST.
Compare 2 ways to travel from Orlando to St. Louis
Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 2 hours and with fares starting at just R 1 793, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and St. Louis?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Compare bus companies
Frequently asked questions about travelling from Orlando to St. Louis by bus
How much does a bus ticket from Orlando to St. Louis cost?
The bus ticket price from Orlando to St. Louis starts at R 1 793. The best way to find cheap bus tickets from Orlando to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Orlando to St. Louis?
The average travel time between Orlando and St. Louis is around 1d 2h, although the fastest bus will take about 20h 15m. This is the time it takes to travel the 1388 km that separates the two cities.
How many daily bus connections are there between Orlando and St. Louis?
The number of buses from Orlando to St. Louis can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Orlando to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Orlando to St. Louis?
When taking the bus from Orlando to St. Louis, you can travel comfortably and safely with FlixBus, Greyhound.
What are the departure and arrival stations when taking the bus from Orlando to St. Louis?
Buses travelling between Orlando and St. Louis leave from Orlando Bus Station or Orlando RedCoach Station and arrive at Gateway Station.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to St. Louis was searched and found on 24 Nov 2025 with a price of R 2 137To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to St. Louis as early as possible.
You can expect to pay from R 2 137 to R 3 615 for a bus ticket from Orlando to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 137, which is on 2025-11-24.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Orlando to St. Louis?
The bus is the cheapest travel choice for this destination
