Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Orlando Bus Station | Gateway Station | Cheapest | ||||
 | Bus | Orlando Bus Station | Gateway Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Gateway Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | The Florida Mall | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 16:27 EST.
Compare 2 ways to travel from Orlando to St. Louis
Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 2 hours and with fares starting at just £79, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and St. Louis?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
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Frequently asked questions about travelling by bus from Orlando to St. Louis
What's the distance between Orlando and St. Louis by coach?
The journey from Orlando to St. Louis by coach covers an approximate distance of 861 miles (1388 km).
How can I travel from Orlando to St. Louis avoiding air travel?
You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to St. Louis was searched and found on 28 Nov 2025 with a price of £92To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to St. Louis as early as possible.
You can expect to pay from £92 to £180 for a bus ticket from Orlando to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at £92, which is on 2025-11-28.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Orlando to St. Louis?
The bus is the cheapest travel choice for this destination
