Find coaches from Philadelphia, PA to Greenville, SC

Next departures

Next departures from Philadelphia to Greenville on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
199 Spring Garden St.
1116 Woodruff RdCheapest
FlixBus
Philadelphia, 199 Spring Garden St
1116 Woodruff RdFastest
Greyhound Lines, Inc. + FlixBus
199 Spring Garden St.
1116 Woodruff RdNo tags
Greyhound Lines, Inc.
199 Spring Garden St.
1116 Woodruff RdNo tags
FlixBus
Philadelphia, 199 Spring Garden St
1116 Woodruff RdNo tags

Last refresh of the prices: Today at 6:00 AM EDT.

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Compare 2 ways to travel from Philadelphia to Greenville

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 18 hours 35 minutes and with fares starting at just US$72, it presents an excellent value for a comfortable ride.

19bus per day
18h 35mAverage duration
849 kmDistance
21kgCO₂ emissions
Bus
Average priceUS$72 - US$220Average duration18h 35m
21kg CO₂e
Train
Average priceUS$128 - US$694Average duration13h 46m
78kg CO₂e

Bus Philadelphia, PA to Greenville, SC: Trip Overview

Average ticket priceUS$96
Average bus trip duration18h 35m
Number of daily buses19
Earliest bus departure02:45
Distance848 km
Latest bus departure23:15

Philadelphia to Greenville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Philadelphia to Greenville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Philadelphia to Greenville.

Discover how much the bus trip from Philadelphia to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Philadelphia, PA - Greenville, SC

  1. How much does a bus ticket from Philadelphia to Greenville cost?

    The bus ticket price from Philadelphia to Greenville starts at US$72. The best way to find cheap bus tickets from Philadelphia to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Philadelphia to Greenville?

    The average travel time between Philadelphia and Greenville is around 18h 35m, although the fastest bus will take about 14h 5m. This is the time it takes to travel the 855 km that separates the two cities.

  3. How many daily bus connections are there between Philadelphia and Greenville?

    The number of buses from Philadelphia to Greenville can differ depending on the day of the week. On average, there are 19 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Philadelphia to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Philadelphia to Greenville?

    When taking the bus from Philadelphia to Greenville, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Philadelphia to Greenville?

    Buses travelling between Philadelphia and Greenville leave from Philadelphia Airport or Independence Travel Center and arrive at Guadalajara Supermarket Bus Stop, Greenville Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$88
29/10
US$94
Today
US$97
31/10
US$88
01/11
US$75
02/11
US$102
03/11
US$81
04/11
US$75
busbud logoThe cheapest trip from Philadelphia, PA to Greenville, SC was searched and found on 01 Nov 2025 with a price of US$75

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Greenville, SC as early as possible.

You can expect to pay from US$75 to US$188 for a bus ticket from Philadelphia, PA to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$75, which is on 2025-11-01.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Philadelphia to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Philadelphia to Greenville.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Philadelphia to Greenville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Philadelphia to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

What's the cheapest way to go from Philadelphia, PA to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Philadelphia, PA by bus?

Bus from Greenville, SC to Philadelphia, PA

You can also go to Greenville, SC by train

Train from Philadelphia, PA to Greenville, SC

Why choose Busbud?

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