Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Pittsburgh Intermodal Station | Des Moines | Cheapest | ||||
 | Bus | Pittsburgh Intermodal Station | Des Moines | Fastest |
Last refresh of the prices: Last Sunday at 2:35 PM EST.
Get from Pittsburgh to Des Moines
The journey takes about 23 hours 50 minutes, and with fares starting at just R 2 183, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pittsburgh and Des Moines?
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Compare bus companies
Based on 87472 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 2 420
Frequently asked questions about travelling from Pittsburgh to Des Moines by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Pittsburgh to Des Moines?
The cheapest bus tickets from Pittsburgh to Des Moines start at R 2 183. The average price for this route is around R 3 366. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Pittsburgh to Des Moines?
The average bus journey time from Pittsburgh to Des Moines is 23h 50m, covering a distance of 1148 km. The fastest bus gets you there in 18h 55m and is operated by Greyhound.
Which bus companies service the Pittsburgh to Des Moines route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Pittsburgh to Des Moines?
The earliest bus departs from Pittsburgh to Des Moines at 00:40. And the latest bus departs at 19:45.
What are the CO₂ emissions for the bus trip from Pittsburgh to Des Moines?
A bus trip from Pittsburgh to Des Moines produces an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to Des Moines was searched and found on 07 Jan 2026 with a price of R 1 859To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Des Moines as early as possible.
You can expect to pay from R 1 859 to R 4 175 for a bus ticket from Pittsburgh to Des Moines based on the last 1 days. You can expect to find the cheapest price for the trip at R 1 859, which is on 2026-01-07.
