Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Roanoke Bus Stop | Indianapolis Bus Station | CheapestFastest | ||||
| Bus | Roanoke Bus Stop | Indianapolis Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Roanoke Bus Stop | Downtown Transit Center | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Roanoke Bus Stop | Downtown Transit Center | No tags |
Last refresh of the prices: Last Sunday at 1:20 PM EST.
Compare 2 ways to travel from Roanoke to Indianapolis
Among the sustainable travel choices, the Train stands out as a good way to reach Indianapolis. The journey takes about 21 hours 17 minutes and with fares starting at just R 1 515, it presents an excellent value for a comfortable ride.
Where are the popular stops in Roanoke and Indianapolis?
Stops in Roanoke
- AExit 140 (Park and Ride), Virginia 24153, USA
Compare bus companies
Based on 87524 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Greyhound ticket prices on this trip start at R 1 565
Greyhound Roanoke Indianapolis recent customer reviews
It was way too cramped...totally sore after this trip
Danny C.
Frequently asked questions about travelling from Roanoke to Indianapolis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Roanoke to Indianapolis?
The cheapest bus tickets from Roanoke to Indianapolis start at R 1 565. The average price for this route is around R 1 888. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Roanoke to Indianapolis?
The average bus journey time from Roanoke to Indianapolis is 19h 35m, covering a distance of 608 km. The fastest bus gets you there in 15h 55m and is operated by Greyhound.
Which bus companies service the Roanoke to Indianapolis route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Roanoke to Indianapolis?
The earliest bus departs from Roanoke to Indianapolis at 04:35. And the latest bus departs at 12:50.
What are the CO₂ emissions for the bus trip from Roanoke to Indianapolis?
A bus trip from Roanoke to Indianapolis produces an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Roanoke to Indianapolis was searched and found on 10 Mar 2026 with a price of R 1 766To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Roanoke to Indianapolis as early as possible.
You can expect to pay from R 1 766 to R 2 615 for a bus ticket from Roanoke to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 766, which is on 2026-03-10.
