Find coaches from Roanoke to Indianapolis

Previously seen journeys

Next departures from Roanoke to Indianapolis on 6 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Roanoke Bus Stop
Downtown Transit CenterNo tags
Greyhound
Roanoke Bus Stop
Indianapolis Bus StationNo tags
Greyhound
Roanoke Bus Stop
Indianapolis Bus StationNo tags
FlixBus + Greyhound
Roanoke Bus Stop
Downtown Transit CenterNo tags
Greyhound
Roanoke Bus Stop
Indianapolis Bus StationNo tags

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Compare 2 ways to travel from Roanoke to Indianapolis

Bus
Average priceUS$66 - US$124Average duration19h 35m
15kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$94 - US$177Average duration23h
55kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Roanoke to Indianapolis

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 19 hours 35 minutes and with fares starting at just US$66, it presents an excellent value for a comfortable ride.

3bus per day
19h 35mAverage duration
US$66Cheapest ticket
15kgCO₂ emissions

Bus Roanoke to Indianapolis: Trip Overview

Average ticket priceUS$82
Average bus trip duration19h 35m
Number of daily buses3
Earliest bus departure04:40
Distance377 miles
Latest bus departure12:50

Roanoke to Indianapolis Bus

With Busbud, comparing and booking tickets for a bus from Roanoke to Indianapolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Roanoke to Indianapolis will be provided by the most trusted bus companies.

Discover how much the bus trip from Roanoke to Indianapolis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Roanoke - Indianapolis

  1. How far is Indianapolis from Roanoke by coach?

    The distance between Roanoke and Indianapolis by coach is approximately 378 miles (609 km).

  2. Is there a way to reach Indianapolis from Roanoke without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/10
No data
05/10
US$139
Today
No data
07/10
No data
08/10
No data
09/10
No data
10/10
No data
11/10
No data
busbud logoThe cheapest trip from Roanoke to Indianapolis was searched and found on 5 Oct 2025 with a price of US$139

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Roanoke to Indianapolis as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Roanoke to Indianapolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Roanoke to Indianapolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Roanoke to Indianapolis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Roanoke to Indianapolis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Roanoke to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Roanoke by bus?

Bus from Indianapolis to Roanoke

You can also go to Indianapolis by train

Train from Roanoke to Indianapolis

Why choose Busbud?

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