Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rochester | Downtown Transit Center | Cheapest | ||||
 | Bus | Rochester | Indianapolis Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Rochester | Indianapolis Bus Station | No tags |
Last refresh of the prices: Yesterday at 2:56 PM EST.
Compare 2 ways to travel from Rochester to Indianapolis
Among the sustainable travel choices, the train stands out as a good way to reach Indianapolis. The journey takes about 1 day, 20 minutes and with fares starting at just R 2 230, it presents an excellent value for a comfortable ride.
Where are the popular stops in Rochester and Indianapolis?
Stops in Rochester
- A186 Cumberland St (Across from the Amtrak Terminal) , Rochester, NY 14605
- BRush Rhees Library, 755 Library Road, Rochester, NY 14627
- C
Rochester Institute of Technology
61 Lomb Memorial Dr, Rochester, NY 14623
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Frequently asked questions about travelling from Rochester, NY, US to Indianapolis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Rochester to Indianapolis?
The cheapest bus tickets from Rochester to Indianapolis start at R 2 016. The average price for this route is around R 3 100. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Rochester to Indianapolis?
The average bus journey time from Rochester to Indianapolis is 1d 3h, covering a distance of 806 km. The fastest bus gets you there in 23h 45m and is operated by Greyhound.
Which bus companies service the Rochester to Indianapolis route?
What is the earliest and latest departure time for the bus from Rochester to Indianapolis?
The earliest bus departs from Rochester to Indianapolis at 00:35. And the latest bus departs at 23:35.
What are the CO₂ emissions for the bus trip from Rochester to Indianapolis?
A bus trip from Rochester to Indianapolis produces an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Rochester to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Rochester to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Rochester to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Rochester to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rochester, NY, US to Indianapolis was searched and found on 18 Dec 2025 with a price of R 2 117To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester, NY, US to Indianapolis as early as possible.
You can expect to pay from R 2 117 to R 3 201 for a bus ticket from Rochester, NY, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 117, which is on 2025-12-18.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
