Find coaches from Rochester, NY, US to Indianapolis

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Today13 Jul
Tomorrow14 Jul
from US$115
Tue15 Jul
from US$95
Wed16 Jul
from US$98
Thu17 Jul
from US$115
Fri18 Jul
from US$123
Sat19 Jul
Sun20 Jul

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 14 July at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: 16 July at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 14 July at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: 15 July at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 14 July at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: 15 July at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 14 July at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: 15 July at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 14 July at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: 15 July at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Rochester to Indianapolis

Bus
Average priceUS$82 - US$200Average duration21h 25m
20kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$91 - US$1,007Average duration1d
73kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Rochester to Indianapolis

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 21 hours 25 minutes and with fares starting at just US$82, it presents an excellent value for a comfortable ride.

3bus per day
21h 25mAverage duration
US$82Cheapest ticket
20kgCO₂ emissions

Bus Rochester to Indianapolis: Trip Overview

Average ticket priceUS$112
Average bus trip duration21h 25m
Number of daily buses3
Earliest bus departure06:10
Distance500 miles
Latest bus departure23:50

Rochester to Indianapolis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Rochester to Indianapolis.

We make it our job to connect you with the most dependable bus companies that cover bus service from Rochester to Indianapolis.

Discover how much the bus trip from Rochester to Indianapolis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Rochester, NY, US - Indianapolis

  1. What's the distance between Rochester and Indianapolis by coach?

    The journey from Rochester to Indianapolis by coach covers an approximate distance of 500 miles (806 km).

  2. How can I travel from Rochester to Indianapolis avoiding air travel?

    To travel from Rochester to Indianapolis without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/07
US$125
12/07
No data
Today
No data
14/07
US$107
15/07
US$87
16/07
US$102
17/07
US$134
18/07
US$125
busbud logoThe cheapest trip from Rochester to Indianapolis was searched and found on 15 Jul 2025 with a price of US$87

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester to Indianapolis as early as possible.

You can expect to pay from US$87 to US$134 for a bus ticket from Rochester to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$87, which is on 2025-07-15.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Rochester to Indianapolis but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Rochester to Indianapolis.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Rochester to Indianapolis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Rochester to Indianapolis while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Rochester to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Rochester by bus?

Bus from Rochester to Indianapolis

You can also go to Indianapolis by train

Train from Rochester, NY, US to Indianapolis

Why choose Busbud?

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