Bus Tickets from Rochester, NY to Indianapolis, IN

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TodayMay 16
TomorrowMay 17
from US$149
SunMay 18
MonMay 19
TueMay 20
WedMay 21
ThuMay 22
FriMay 23

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 17 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: May 18 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 17 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: May 18 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 17 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: May 18 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 17 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: May 18 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 17 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: May 19 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Today at 1:50 AM EDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Rochester to Indianapolis

Bus
Average PriceUS$107 - US$255Average Duration23h 45m
20kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$207 - US$207Average Duration1d
73kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Rochester to Indianapolis

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 23 hours 45 minutes, and with fares starting at just US$107, it presents an excellent value for a comfortable ride.

6bus per day
23h 45mAverage Duration
US$107Cheapest ticket
20kgCO₂ emissions

Bus Rochester to Indianapolis: Trip Overview

Average Ticket PriceUS$171
Average Bus Trip Duration23h 45m
Number of daily buses6
Earliest bus departure12:35am
Distance806 km
Latest bus departure11:50pm

Rochester to Indianapolis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Rochester to Indianapolis.

We make it our job to connect you with the most dependable bus companies that cover bus service from Rochester to Indianapolis.

Discover how much the bus trip from Rochester to Indianapolis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Rochester - Indianapolis

  1. How long is the bus ride from Rochester to Indianapolis?

    The typical travel time from Rochester to Indianapolis by bus is around 23h 45m. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 18h 25m.

  2. How far is Rochester from Indianapolis?

    Rochester and Indianapolis are 806 km (500 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Rochester to Indianapolis?

    Buses departing from Bus Station in Rochester will take you to Greyhound Amtrak Station in Indianapolis.

  4. What is the cheapest way to get from Rochester to Indianapolis?

    The least expensive option to go from Rochester to Indianapolis would be going by bus. Starting at US$107, this bus is the most cost-effective option for your journey.

  5. How much does it cost to take the bus from Rochester to Indianapolis?

    The bus from Rochester to Indianapolis will cost you US$171, on average.

  6. Can I take an overnight bus from Rochester to Indianapolis?

    Yes! If you're heading from Rochester to Indianapolis, you'll find buses departing until 11:50pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-14
No data
05-15
No data
Today
No data
05-17
US$155
05-18
No data
05-19
No data
05-20
No data
05-21
No data
busbud logoThe cheapest trip from Rochester to Indianapolis was searched and found on May 17, 2025 with a price of US$155

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester to Indianapolis, as early as possible.

You can expect to pay from US$155 to US$208 for a bus ticket from Rochester to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$155 which is on 2025-05-17.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Rochester to Indianapolis but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Rochester to Indianapolis.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Rochester to Indianapolis will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Rochester to Indianapolis while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Rochester to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Rochester by bus?

Bus from Rochester to Indianapolis

You can also go to Indianapolis by train

Train from Rochester to Indianapolis

Why choose Busbud?

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