Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Rochester | Indianapolis Bus Station | CheapestFastest | ||||
| Bus
| Rochester | Indianapolis Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Rochester | Indianapolis (W Vermont St) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Rochester | Indianapolis (W Vermont St) | No tags |
Last refresh of the prices: Yesterday at 1:20 PM EDT.
Compare 2 ways to go from Rochester to Indianapolis
Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 16 hours, and with fares starting at just COP 253,675, it presents an excellent value for a comfortable ride.
Bus stations and stops in Rochester and Indianapolis
Stops in Rochester
- A
Bus Station
186 Cumberland St (Across from the Amtrak Terminal) , Rochester, NY 14605 - B
U of R
Rush Rhees Library, 755 Library Road, Rochester, NY 14627 - C
Rochester Institute of Technology
61 Lomb Memorial Dr, Rochester, NY 14623
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Frequently asked questions about travelling from Rochester, NY, US to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rochester to Indianapolis?
The cheapest bus tickets from Rochester to Indianapolis start from COP 253,675. The average price for this route is around COP 361,543. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rochester to Indianapolis?
The average bus travel time from Rochester to Indianapolis is 16h, covering a distance of 806 km. The quickest bus can get you there in 13h 15m and is operated by Greyhound.
Which bus companies service the Rochester to Indianapolis route?
What are the earliest and latest departure times for the bus from Rochester to Indianapolis?
The earliest bus departs from Rochester to Indianapolis at 6:10am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from Rochester to Indianapolis?
A bus trip from Rochester to Indianapolis generates an estimated 20.1498 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Rochester to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88213 reviews.
Which bus company has the best Wi-Fi from Rochester to Indianapolis?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Rochester to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Rochester to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rochester, NY, US to Indianapolis was searched and found on Oct 17, 2026 with a price of COP 302,136To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester, NY, US to Indianapolis, as early as possible.
You can expect to pay from COP 302,136 to COP 472,058 for a bus ticket from Rochester, NY, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at COP 302,136 which is on 2026-10-17.
What's the cheapest way to go from Rochester, NY, US to Indianapolis?
The Bus is the cheapest travel choice for this destination
