Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Chicago 95Th & Dan Ryan | Cheapest | ||||
 | Bus | Tornado I-35 | Chicago, IL | Fastest | ||||
Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Downtown Greyhound Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Downtown Greyhound Station | No tags | ||||
Valley Transit + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Downtown Greyhound Station | No tags |
Last refresh of the prices: Yesterday at 4:31 AM CST.
Compare 2 ways to travel from San Antonio to Chicago
Among the sustainable travel choices, the Bus stands out as a good way to reach Chicago. The journey takes about 1 day, 7 hours 35 minutes and with fares starting at just R 1 545, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Antonio and Chicago?
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C4407 S PanAm Expy #101, San Antonio, TX 78225, USA
- D165 Bowie St, San Antonio, 78205
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- B
Chicago O'Hare International Airport
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Frequently asked questions about travelling from San Antonio, US to Chicago by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from San Antonio to Chicago?
The cheapest bus tickets from San Antonio to Chicago start at R 1 545. The average price for this route is around R 2 656. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from San Antonio to Chicago?
The average bus journey time from San Antonio to Chicago is 1d 7h, covering a distance of 1693 km. The fastest bus gets you there in 22h 45m and is operated by Tornado Bus.
Which bus companies service the San Antonio to Chicago route?
Several major bus companies operate on this route with 27 buses available per day, including services from Tornado Bus, Greyhound, FlixBus, Valley Transit.
What is the earliest and latest departure time for the bus from San Antonio to Chicago?
The earliest bus departs from San Antonio to Chicago at 01:30. And the latest bus departs at 21:15.
What are the CO₂ emissions for the bus trip from San Antonio to Chicago?
A bus trip from San Antonio to Chicago produces an estimated 42 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from San Antonio to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87518 reviews.
Which bus company has the best Wi-Fi from San Antonio to Chicago?
Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 3.9.
Which bus company offers the most punctual service from San Antonio to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Antonio to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Antonio, US to Chicago was searched and found on 09 Feb 2026 with a price of R 2 189To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Chicago as early as possible.
You can expect to pay from R 2 189 to R 5 026 for a bus ticket from San Antonio, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 189, which is on 2026-02-09.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
