Next departures from San Antonio to Chicago on 28 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Chicago 95Th & Dan Ryan
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures from San Antonio to Chicago on 29 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Tornado I-35
Chicago, IL
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures from San Antonio to Chicago on 30 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures from San Antonio to Chicago on 1 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Downtown Greyhound Station
No tags
Bus
Tornado I-35
Chicago, IL
No tags
Next departures from San Antonio to Chicago on 2 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
537-517 W. Jackson Blvd
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Bus
Tornado I-35
Chicago, IL
No tags
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Next departures from San Antonio to Chicago on 3 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Valley Transit + Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Chicago 95Th & Dan Ryan
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Downtown Greyhound Station
No tags
Next departures from San Antonio to Chicago on 4 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
Cheapest
Conexiones + Tornado Bus
Bus
Tornado I-35
Chicago, IL
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Downtown Greyhound Station
No tags
Last refresh of the prices: Today at 20:17 CST.
Compare 2 ways to travel from San Antonio to Chicago
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 6 hours 55 minutes and with fares starting at just £83, it presents an excellent value for a comfortable ride.
Based on 156 reviews, the company was rated 3.1 stars on Busbud. Travellers were especially satisfied with the value for money and the ticket access but often complained with the timeliness. Tornado Bus ticket prices on this trip start at £200
Based on 87398 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £87
Greyhound San Antonio Chicago recent customer reviews
Leaving from Memphis we back tracked to Arkansas. The bus driver kept stopping and not letting anyone know what's going on. I even asked her what was going on and why we kept stopping and she ignored me. The bus broke down 2 hrs away from Chicago. We were supposed to arrive in Chicago downtown around 6am and did not arrive until after 10am. I also paid for two seats for me and my child and he had to sit on my lap because the bus was so crowded and uncomfortable.
1 out of 5 stars
Ashley F.
The Bus was very hot the driver kepts stopping to go to the bathroom the bus broke down & finally the driver wouldnt take me to the stopping point he said that was the end of where was going. Not according to what was purchased. Had to walk rest of the way. I was not satisfied with this service at all. I am a musician performer travel all the time meet a lot of people & all my fans musician friends & relatives will be hearing about why not to book with this company. Unsatisfied Customer.
Based on 11454 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £100
Based on 33 reviews, the company was rated 3 stars on Busbud. Travellers were especially satisfied with the departure location and the staff but often complained with the Wi-Fi. Valley Transit ticket prices on this trip start at £77
Frequently asked questions about travelling by bus from San Antonio, US to Chicago
How far is Chicago from San Antonio by coach?
The distance between San Antonio and Chicago by coach is approximately 1050 miles (1693 km).
Is there a way to reach Chicago from San Antonio without flying?
You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
24/11
£205
25/11
£205
Today
£253
27/11
£205
28/11
£205
29/11
£205
30/11
£205
01/12
£205
The cheapest trip from San Antonio, US to Chicago was searched and found on 27 Nov 2025 with a price of £205
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Chicago as early as possible.
You can expect to pay from £205 to £344 for a bus ticket from San Antonio, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £205, which is on 2025-11-27.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.