Bus Tickets from San Antonio, TX to Chicago, IL

Find affordable bus tickets from San Antonio, TX to Chicago, IL with flexible options. Book your trip now

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TodayMay 12
TomorrowMay 13
from $196
WedMay 14
from $118
ThuMay 15
from $116
FriMay 16
SatMay 17
SunMay 18
MonMay 19

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 13 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 15 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc.
    Greyhound Lines Mexico + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 13 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 14 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc.
    Greyhound Lines Mexico + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 13 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 14 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc.
    Greyhound Lines Mexico + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 13 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 14 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 13 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 14 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
    Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from San Antonio to Chicago.

Bus
Average Price$73 - $417Average Duration1d 5h
42kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$139 - $712Average Duration1d 9h
154kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Antonio to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 5 hours 55 minutes and with fares starting at just $73, it presents an excellent value for a comfortable ride.

18bus per day
1d 5hAverage Duration
$73Cheapest ticket
42kgCO₂ emissions

Bus San Antonio to Chicago: Trip Overview

Average ticket price$226
Average bus trip duration1d 5h
Number of daily buses18
Earliest bus departure1:30am
Distance1052 miles (1696 km)
Latest bus departure9:45pm

San Antonio to Chicago Bus

With Busbud, comparing and booking tickets for a bus from San Antonio to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Antonio to Chicago.

Discover how much the bus trip from San Antonio to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip San Antonio - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/10
$174
05/11
$238
Today
$222
05/13
$216
05/14
$173
05/15
$163
05/16
No data
05/17
No data
busbud logoThe cheapest trip from San Antonio to Chicago was searched and found on May 15, 2025 with a price of $163

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio to Chicago, as early as possible.

You can expect to pay from $163 to $276 for a bus ticket from San Antonio to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $163 which is on 2025-05-15.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Antonio to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Antonio to Chicago.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Antonio to Chicago will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from San Antonio to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to San Antonio by bus?

Bus from San Antonio to Chicago

You can also go to Chicago by train

Train from San Antonio to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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