Next departures from San Antonio to Indianapolis on 6 January
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
Cheapest
Bus
San Antonio Bus Station
Indianapolis Bus Station
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Downtown Transit Center
No tags
Next departures from San Antonio to Indianapolis on 7 January
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Downtown Transit Center
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Downtown Transit Center
No tags
Next departures from San Antonio to Indianapolis on 8 January
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Downtown Transit Center
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
Next departures from San Antonio to Indianapolis on 9 January
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Downtown Transit Center
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
Next departures from San Antonio to Indianapolis on 11 January
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Indianapolis Bus Station
No tags
Valley Transit + Greyhound Lines, Inc. + FlixBus
Bus
San Antonio Bus Station
Downtown Transit Center
No tags
Last refresh of the prices: Today at 4:32 PM CST.
Compare 2 ways to travel from San Antonio to Indianapolis
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 1 day, 6 hours 30 minutes and with fares starting at just R 1 874, it presents an excellent value for a comfortable ride.
Based on 87483 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 1 899
Based on 37 reviews, the company was rated 2.9 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the value for money. Valley Transit ticket prices on this trip start at R 1 966
Based on 11928 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 2 192
Frequently asked questions about travelling from San Antonio, US to Indianapolis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from San Antonio to Indianapolis?
The cheapest bus tickets from San Antonio to Indianapolis start at R 1 874. The average price for this route is around R 3 275. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from San Antonio to Indianapolis?
The average bus journey time from San Antonio to Indianapolis is 1d 6h, covering a distance of 1608 km. The fastest bus gets you there in 1d 2h and is operated by Greyhound.
Which bus companies service the San Antonio to Indianapolis route?
Several major bus companies operate on this route with 13 buses available per day, including services from Greyhound, Valley Transit, FlixBus.
What is the earliest and latest departure time for the bus from San Antonio to Indianapolis?
The earliest bus departs from San Antonio to Indianapolis at 01:30. And the latest bus departs at 21:15.
What are the CO₂ emissions for the bus trip from San Antonio to Indianapolis?
A bus trip from San Antonio to Indianapolis produces an estimated 40 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from San Antonio to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from San Antonio to Indianapolis?
Based on reviews on Busbud, the bus company Valley Transit has the best Wi-Fi rating with a score of 2.8.
Which bus company offers the most punctual service from San Antonio to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Antonio to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
03/01
R 4 111
04/01
R 5 571
Today
R 4 413
06/01
R 4 262
07/01
R 2 802
08/01
R 3 256
09/01
R 2 802
10/01
R 2 937
The cheapest trip from San Antonio, US to Indianapolis was searched and found on 07 Jan 2026 with a price of R 2 802
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Indianapolis as early as possible.
You can expect to pay from R 2 802 to R 5 571 for a bus ticket from San Antonio, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 802, which is on 2026-01-07.
What's the cheapest way to go from San Antonio, US to Indianapolis?
The bus is the cheapest travel choice for this destination