Bus Tickets from San Antonio, TX to Indianapolis, IN

Find affordable bus tickets from San Antonio, TX to Indianapolis, IN with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 14
from $145
TomorrowMay 15
FriMay 16
SatMay 17
SunMay 18
MonMay 19
TueMay 20
WedMay 21

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 14 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 16 at
    Destination city: Indianapolis
    Destination location: Indianapolis Northeast
    Operated by: Valley Transit Co., Inc. + Greyhound Lines, Inc. + FlixBus
    Valley Transit Co., Inc. + Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 14 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 15 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 15 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 16 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Valley Transit Co., Inc. + Greyhound Lines, Inc.
    Valley Transit Co., Inc. + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 15 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from San Antonio to Indianapolis.

Average Price$120 - $337Average Duration1d 7h
40kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average Price$353 - $367Average Duration1d 16h
146kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Antonio to Indianapolis

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 1 day, 7 hours 40 minutes and with fares starting at just $120, it presents an excellent value for a comfortable ride.

10bus per day
1d 7hAverage Duration
$120Cheapest ticket
40kgCO₂ emissions

Bus San Antonio to Indianapolis: Trip Overview

Average ticket price$176
Average bus trip duration1d 7h
Number of daily buses10
Earliest bus departure1:30am
Distance997 miles (1607 km)
Latest bus departure9:45pm

San Antonio to Indianapolis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Antonio to Indianapolis.

Bus service from San Antonio to Indianapolis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Indianapolis from San Antonio, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip San Antonio - Indianapolis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/12
$269
05/13
No data
Today
$175
05/15
No data
05/16
No data
05/17
No data
05/18
No data
05/19
$111
busbud logoThe cheapest trip from San Antonio to Indianapolis was searched and found on May 19, 2025 with a price of $111

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio to Indianapolis, as early as possible.

You can expect to pay from $111 to $269 for a bus ticket from San Antonio to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $111 which is on 2025-05-19.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Antonio to Indianapolis but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from San Antonio to Indianapolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Antonio to Indianapolis.

Tune out to the fine sounds of your best music playlist on your bus trip from San Antonio to Indianapolis while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from San Antonio to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Antonio by bus?

Bus from San Antonio to Indianapolis

You can also go to Indianapolis by train

Train from San Antonio to Indianapolis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting San Antonio

Buses Leaving from San Antonio

Buses Going to San Antonio

Popular Buses Connecting Indianapolis

Buses Leaving from Indianapolis

Buses Going to Indianapolis