Bus from Syracuse, US to Chicago: Tickets & Timetables

Next bus departures

Next departures from Syracuse to Chicago on 18 April
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Chicago 95Th & Dan RyanCheapest
Greyhound Lines, Inc.Bus
Syracuse (Regional Transportation Center)
Downtown Greyhound StationFastest
Greyhound Lines, Inc.Bus
Syracuse (Regional Transportation Center)
Downtown Greyhound StationNo tags
Greyhound Lines, Inc.Bus
Syracuse (Regional Transportation Center)
537-517 W. Jackson BlvdNo tags
Greyhound Lines, Inc.Bus
Syracuse (Regional Transportation Center)
Chicago 95Th & Dan RyanNo tags

Last refresh of the prices: Yesterday at 10:50 PM EDT.

Compare 2 ways to travel from Syracuse to Chicago

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 13 hours 7 minutes and with fares starting at just CZK 1 248, it presents an excellent value for a comfortable ride.

1train per day
13h 7mAverage duration
950 kmDistance
86kgCO₂ emissions
Average priceCZK 1 479 - CZK 8 932Average duration1d 1h
24kg CO₂e
Average priceCZK 1 248 - CZK 4 565Average duration13h 7m
86kg CO₂e

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
15/04
CZK 2 993
16/04
CZK 3 331
Today
CZK 3 489
18/04
CZK 3 404
19/04
CZK 2 920
20/04
CZK 2 161
21/04
CZK 2 066
22/04
CZK 1 950
busbud logoThe cheapest trip from Syracuse, US to Chicago was searched and found on 22 Apr 2026 with a price of CZK 1 950

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Chicago as early as possible.

You can expect to pay from CZK 1 950 to CZK 4 469 for a bus ticket from Syracuse, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at CZK 1 950, which is on 2026-04-22.

What's the cheapest way to go from Syracuse, US to Chicago?

busbud logoThe Bus is the cheapest travel choice for this destination

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