How much is the bus ticket from Syracuse to Chicago?

The cheapest bus tickets from Syracuse to Chicago start from $64. The average price for this route is around $90. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Syracuse to Chicago?

The average bus trip duration from Syracuse to Chicago is 1d 4h, covering a distance of 589 miles (950 km). The quickest bus can get you there in 16h 35m and is operated by Greyhound .

Which bus companies service the Syracuse to Chicago route?

Several major bus companies operate on this route with 11 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Syracuse to Chicago?

The earliest bus departs from Syracuse to Chicago at 3:20am. And the latest bus departs at 9:00pm.

What are the CO₂ emissions for the bus trip from Syracuse to Chicago?

A bus trip from Syracuse to Chicago generates an estimated 23.74245 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Syracuse to Chicago?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87532 reviews.

Which bus company has the best Wi-Fi from Syracuse to Chicago?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Syracuse to Chicago?

According to Busbud traveler reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Syracuse to Chicago?

According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Syracuse to Chicago from $64 | Refundable Tickets

Next bus departures

Next departures for Syracuse to Chicago on April 11
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:30am	Syracuse (Regional Transportation Center)	20h 5m	11:35pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	4:30am	Syracuse (Regional Transportation Center)	16h 35m	8:05pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	8:30am	Syracuse (Regional Transportation Center)	1d 2h	10:00am	Downtown Greyhound Station	No tags
	Bus	3:00pm	Syracuse (Regional Transportation Center)	23h 25m	1:25pm	Downtown Greyhound Station	No tags
	Bus	4:30am	Syracuse (Regional Transportation Center)	1d 4h	8:00am	537-517 W. Jackson Blvd	No tags

Last refresh of the prices: Today at 12:13 AM EDT.

Compare 2 ways to go from Syracuse to Chicago

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 13 hours 7 minutes and with fares starting at just $60, it presents an excellent value for a comfortable ride.

1train per day

13h 7mAverage Duration

589 milesDistance

86kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$64 - $424	Average Duration1d 4h	CO₂ emissions 24kg CO₂e
Train	Average Price$60 - $866	Average Duration13h 7m	CO₂ emissions 86kg CO₂e

Where are the popular stops in Syracuse and Chicago?

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

Greyhound

3.5/587,533 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/512,446 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, Greyhound, BlaBlaCar Bus, Intercape, ALSA, Trenitalia, Big Sky

Frequently asked questions about traveling from Syracuse, US to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Syracuse to Chicago?
The cheapest bus tickets from Syracuse to Chicago start from $64. The average price for this route is around $90. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Chicago?
The average bus trip duration from Syracuse to Chicago is 1d 4h, covering a distance of 589 miles (950 km). The quickest bus can get you there in 16h 35m and is operated by Greyhound.
Which bus companies service the Syracuse to Chicago route?
Several major bus companies operate on this route with 11 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Syracuse to Chicago?
The earliest bus departs from Syracuse to Chicago at 3:20am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Chicago?
A bus trip from Syracuse to Chicago generates an estimated 23.74245 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Syracuse to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87532 reviews.
Which bus company has the best Wi-Fi from Syracuse to Chicago?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Syracuse to Chicago?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Chicago?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

04/08

$153

04/09

$158

Today

$170

04/11

$155

04/12

$135

04/13

$97

04/14

$97

04/15

$93

The cheapest trip from Syracuse, US to Chicago was searched and found on Apr 15, 2026 with a price of $93

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Chicago, as early as possible.

You can expect to pay from $93 to $242 for a bus ticket from Syracuse, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $93 which is on 2026-04-15.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.