Bus from Syracuse, US to Chicago: Tickets & Schedules

Next bus departures

Next departures for Syracuse to Chicago on July 16
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Syracuse (Regional Transportation Center)
Downtown Greyhound StationCheapest
Greyhound Lines, Inc.Bus
Syracuse (Regional Transportation Center)
Downtown Greyhound StationFastest
Greyhound Lines, Inc.Bus
Syracuse (Regional Transportation Center)
537-517 W. Jackson BlvdNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Chicago 95Th & Dan RyanNo tags
Greyhound Lines, Inc.Bus
Syracuse (Regional Transportation Center)
Chicago 95Th & Dan RyanNo tags

Last refresh of the prices: Today at 5:35 PM EDT.

Compare 2 ways to go from Syracuse to Chicago

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 13 hours 7 minutes, and with fares starting at just $104, it presents an excellent value for a comfortable ride.

1train per day
13h 7mAverage Duration
950 kmDistance
86kgCO₂ emissions
Bus
Average Price$99 - $327Average Duration18h 50m
24kg CO₂e
Train
Average Price$104 - $312Average Duration13h 7m
86kg CO₂e

Frequently asked questions about travelling from Syracuse, US to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Syracuse to Chicago?

    The cheapest bus tickets from Syracuse to Chicago start from $99. The average price for this route is around $130. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Syracuse to Chicago?

    The average bus travel time from Syracuse to Chicago is 18h 50m, covering a distance of 951 km. The quickest bus can get you there in 15h 25m and is operated by Greyhound.

  3. Which bus companies service the Syracuse to Chicago route?

    Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, FlixBus.

  4. What are the earliest and latest departure times for the bus from Syracuse to Chicago?

    The earliest bus departs from Syracuse to Chicago at 4:30am. And the latest bus departs at 7:35pm.

  5. What are the CO₂ emissions for the bus trip from Syracuse to Chicago?

    A bus trip from Syracuse to Chicago generates an estimated 23.76655 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Syracuse to Chicago?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87579 reviews.

  7. Which bus company has the best Wi-Fi from Syracuse to Chicago?

    Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

  8. Which bus company has the best on-time performance from Syracuse to Chicago?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Syracuse to Chicago?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-13
$205
07-14
$201
Today
$193
07-16
$216
07-17
$196
07-18
$114
07-19
$163
07-20
$141
busbud logoThe cheapest trip from Syracuse, US to Chicago was searched and found on Jul 18, 2026 with a price of $114

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Chicago, as early as possible.

You can expect to pay from $114 to $317 for a bus ticket from Syracuse, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $114 which is on 2026-07-18.

What's the cheapest way to go from Syracuse, US to Chicago?

busbud logoThe Bus is the cheapest travel choice for this destination

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