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- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: FastestDeparture time: 12 May atDeparture city: SyracuseDeparture location: Syracuse (Regional Transportation Center)Arrival time: 12 May atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: 12 May atDeparture city: SyracuseDeparture location: Syracuse (Regional Transportation Center)Arrival time: 12 May atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: 12 May atDeparture city: SyracuseDeparture location: Syracuse (Regional Transportation Center)Arrival time: 13 May atDestination city: ChicagoDestination location: Chicago 95Th & Dan RyanOperated by: FlixBus
Vehicle: BusDuration:
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Compare 2 ways to travel from Syracuse to Chicago
Busbud recommends taking the bus from Syracuse to ChicagoAmong the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 23 hours 50 minutes and with fares starting at just US$67, it presents an excellent value for a comfortable ride.
Bus Syracuse to Chicago: Trip Overview
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Syracuse to Chicago Bus
Busbud helps you find a bus from Syracuse to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Syracuse to Chicago from the most reliable bus companies operating this trip.
Discover how much the bus trip from Syracuse to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Syracuse and Chicago?
Frequently asked questions on the trip Syracuse - Chicago
What is the affordable way to go from Syracuse to Chicago?
For coach travel from Syracuse to Chicago, ticket prices typically start at US$67 and can reach a maximum of US$246. These prices can change depending on factors like the date, the class and the coach company you choose. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.
How long does it take to travel from Syracuse to Chicago by bus?
The average duration for a trip from Syracuse to Chicago by coach is around 23h 50m. The fastest coach journey typically takes 16h 35m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.
When is the first coach from Syracuse to Chicago?
The first departure to Chicago is at 04:30. Keep in mind that departure times might change on weekends and holidays.
How far is Chicago from Syracuse by coach?
The distance between Syracuse and Chicago by coach is approximately 592 miles (954 km).
Is there a way to reach Chicago from Syracuse without flying?
You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Is there am overnight coach from Syracuse to Chicago?
Yes, you can find coaches leaving until 21:00 and arriving the next day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse to Chicago was searched and found on 10 May 2025 with a price of US$71To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to Chicago as early as possible.
You can expect to pay from US$71 to US$462 for a bus ticket from Syracuse to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$76, which is on 2025-05-15.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Syracuse and Chicago!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Syracuse to Chicago, get comfy and count the stars.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Syracuse to Chicago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Syracuse to Chicago.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
What's the cheapest way to go from Syracuse to Chicago?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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