Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Niagara Frontier Transportation Authority | Gateway Station | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Niagara Frontier Transportation Authority | Gateway Station | Fastest | ||||
 | Bus | Niagara Frontier Transportation Authority | Gateway Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Niagara Frontier Transportation Authority | Gateway Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Buffalo (BUF) Airport | Gateway Station | No tags |
Last refresh of the prices: Last Saturday at 11:39 AM EST.
Compare 2 ways to travel from Buffalo to St. Louis
Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 19 hours 28 minutes and with fares starting at just R 2 975, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and St. Louis?
Stops in Buffalo
- A
Buffalo Airport
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
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Frequently asked questions about travelling from Buffalo, NY to St. Louis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Buffalo to St. Louis?
The cheapest bus tickets from Buffalo to St. Louis start at R 2 441. The average price for this route is around R 3 081. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Buffalo to St. Louis?
The average bus journey time from Buffalo to St. Louis is 1d 10h, covering a distance of 1077 km. The fastest bus gets you there in 1d 1h and is operated by FlixBus.
Which bus companies service the Buffalo to St. Louis route?
What is the earliest and latest departure time for the bus from Buffalo to St. Louis?
The earliest bus departs from Buffalo to St. Louis at 00:55. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Buffalo to St. Louis?
A bus trip from Buffalo to St. Louis produces an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Buffalo to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Buffalo to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Buffalo to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to St. Louis was searched and found on 14 Dec 2025 with a price of R 1 954To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to St. Louis as early as possible.
You can expect to pay from R 1 954 to R 4 980 for a bus ticket from Buffalo, NY to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 559, which is on 2025-12-17.
What's the cheapest way to go from Buffalo, NY to St. Louis?
The bus is the cheapest travel choice for this destination
