- Florence to Indianapolis buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Florence, SC | Downtown Transit Center | No tags | ||||
FlixBus + Greyhound | Bus | Florence, SC | Indianapolis Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Florence, SC | Indianapolis Bus Station | No tags | ||||
![]() | Bus | Florence, SC | Downtown Transit Center | No tags | ||||
FlixBus + Greyhound | Bus | Florence, SC | Indianapolis Bus Station | No tags |
Compare 2 ways to go from Florence to Indianapolis
Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 1 day, 2 hours 10 minutes and with fares starting at just $166, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Indianapolis?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Florence, SC, US to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Indianapolis?
The cheapest bus tickets from Florence to Indianapolis start from $166. The average price for this route is around $186. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Indianapolis?
The average bus trip duration from Florence to Indianapolis is 1d 2h, covering a distance of 521 miles (841 km). The quickest bus can get you there in 1d 3h and is operated by FlixBus.
Which bus companies service the Florence to Indianapolis route?
Several major train operators operate on this route with 7 trains available per day.
What is the earliest and latest departure time for the bus from Florence to Indianapolis?
The earliest bus departs from Florence to Indianapolis at 12:05am. And the latest bus departs at 4:15pm.
What are the CO₂ emissions for the bus trip from Florence to Indianapolis?
A bus trip from Florence to Indianapolis generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






