Next departures for Florence to Palermo on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Florence (Villa Costanza)
Terminal Bus Palermo
CheapestFastest
Next departures for Florence to Palermo on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Florence (Villa Costanza)
Terminal Bus Palermo
Cheapest
Bus
Terminal Bus Villa Constanza
Terminal Bus Palermo
Fastest
Bus
Florence (Villa Costanza)
Terminal Bus Palermo
No tags
Bus
Florence (Villa Costanza)
Terminal Bus Palermo
No tags
Last refresh of the prices: Yesterday at 3:03 PM CET.
Compare 2 ways to go from Florence to Palermo
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Palermo. The journey takes about 16 hours 25 minutes and with fares starting at just $28, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 450 reviews, the company was rated 4.3 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. Autoservizi Salemi ticket prices on this trip start at $95
Based on 945 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the timeliness. Itabus ticket prices on this trip start at $61
Frequently asked questions about traveling from Florence to Palermo by bus
What is the distance between Florence and Palermo?
About 406 miles (654 km) separate Florence and Palermo.
What are the departure and arrival stations when taking the bus from Florence to Palermo?
If you're headed to Palermo from Florence, chances are that your bus will leave from Terminal Bus Villa Constanza and arrive at Terminal Bus Palermo. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Palermo?
Once in Palermo, you can start exploring the city and discover its surroundings. The top sights and things to do are Cattedrale di Palermo, Palazzo dei Normanni, Galleria Regionale della Sicilia, Cappella Palatina and Orto Botanico.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
$85
11/19
$73
Today
$99
11/21
$35
11/22
No data
11/23
No data
11/24
$91
11/25
$44
The cheapest trip from Florence to Palermo was searched and found on Nov 21, 2025 with a price of $35
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Palermo, as early as possible.
You can expect to pay from $35 to $124 for a bus ticket from Florence to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $35 which is on 2025-11-21.
What's the cheapest way to go from Florence to Palermo?
The bus is the cheapest travel choice for this destination
The cheapest trip from Florence to Palermo was searched and found on Nov 21, 2025 with a price of $35
The bus is the cheapest travel choice for this destination
