Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Florence (Villa Costanza) | Terminal Bus Palermo | Cheapest | ||||
 | Bus | Terminal Bus Villa Constanza | Terminal Bus Palermo | Fastest | ||||
| Bus | Florence (Villa Costanza) | Terminal Bus Palermo | No tags | ||||
| Bus | Florence (Villa Costanza) | Terminal Bus Palermo | No tags |
Last refresh of the prices: Yesterday at 5:23 AM CET.
Compare 2 ways to go from Florence to Palermo
Among the sustainable travel choices, the bus stands out as a good way to reach Palermo. The journey takes about 16 hours 25 minutes, and with fares starting at just $40, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$40 - $275 | Average Duration16h 25m | 16kg CO₂e | ||
Carpool | Average Price$168 - $168 | Average Duration13h | 27kg CO₂e |
Where are the popular stops in Florence and Palermo?
Stops in Florence
- AA1 - Autostrada del Sole, 50018 Scandicci FI, Italy
- B
Florence - Piazzale Montelungo
50129 Centro Storico FI, Italy - DVia della Costituzione, 185, 50018 Scandicci FI, Italy
- EPiazza della Stazione 45, 50123 Firenze, Italy
- FVia Cassia, 49B, 50023 Impruneta FI, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
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Frequently asked questions about travelling from Florence to Palermo by bus
What is the distance between Florence and Palermo?
The distance between Florence and Palermo is around 654 km (406 miles).
What are the departure and arrival locations for buses traveling from Florence to Palermo?
Buses traveling this route start their trip at Terminal Bus Villa Constanza, in Florence, and end it at Terminal Bus Palermo, in Palermo.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence to Palermo was searched and found on Nov 21, 2025 with a price of $51To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Palermo, as early as possible.
You can expect to pay from $51 to $177 for a bus ticket from Florence to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $64 which is on 2025-11-25.
What's the cheapest way to go from Florence to Palermo?
The bus is the cheapest travel choice for this destination
