Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Luzern | PRG Airport | Cheapest | ||||
| Bus | Luzern | Prague (Na Knížecí) | Fastest | ||||
| Bus | Luzern | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luzern | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Luzern | Prague (Central Bus Station Florenc) | No tags |
Last refresh of the prices: Today at 12:12 AM CET.
Get from Lucerne to Prague
The journey takes about 18 hours and with fares starting at just $50, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lucerne and Prague?
Stops in Lucerne
- AEuropaplatz, 6005 Luzern, Switzerland
- B
Lucerne Carparkplatz Inseliquai
Inseliquai, 6005 Luzern, Switzerland - C
Luzern Omnibusbahnhof
Luzern,, Switzerland
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- B
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - CChlumecká, 198 00 Praha 20, Czech Republic
- DKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- ETomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- F300/8 Wilsonova, 110 00 Praha, Czechia
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Frequently asked questions about traveling from Lucerne to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lucerne to Prague?
The cheapest bus tickets from Lucerne to Prague start from $50. The average price for this route is around $74. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lucerne to Prague?
The average bus trip duration from Lucerne to Prague is 18h, covering a distance of 349 miles (563 km). The quickest bus can get you there in 11h 8m and is operated by RegioJet.
Which bus companies service the Lucerne to Prague route?
What is the earliest and latest departure time for the bus from Lucerne to Prague?
The earliest bus departs from Lucerne to Prague at 1:30am. And the latest bus departs at 7:20pm.
What are the CO₂ emissions for the bus trip from Lucerne to Prague?
A bus trip from Lucerne to Prague generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Lucerne to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1057 reviews.
Which bus company has the best Wi-Fi from Lucerne to Prague?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Lucerne to Prague?
According to Busbud traveller reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Lucerne to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lucerne to Prague was searched and found on Nov 30, 2025 with a price of $48To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lucerne to Prague, as early as possible.
You can expect to pay from $48 to $134 for a bus ticket from Lucerne to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $48 which is on 2025-11-30.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
