- Madison to Tupelo buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | North Lake St | Tupelo (Brothers Quick Stop) | No tags | ||||
Greyhound + FlixBus | Bus | North Lake St | Tupelo (Brothers Quick Stop) | No tags | ||||
![]() | Bus | Dutch Mill Park & Ride | Tupelo (Brothers Quick Stop) | No tags | ||||
FlixBus + Greyhound | Bus | North Lake St | Tupelo (Brothers Quick Stop) | No tags | ||||
![]() | Bus | Dutch Mill Park & Ride | Tupelo (Brothers Quick Stop) | No tags |
Get from Madison to Tupelo
The journey takes about 17 hours and with fares starting at just $155, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Madison, WI to Tupelo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Madison to Tupelo?
The cheapest bus tickets from Madison to Tupelo start from $155. The average price for this route is around $155. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Madison to Tupelo?
The average bus trip duration from Madison to Tupelo is 17h, covering a distance of 611 miles (985 km). The quickest bus can get you there in 16h 55m and is operated by Greyhound.
Which bus companies service the Madison to Tupelo route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Madison to Tupelo?
The earliest bus departs from Madison to Tupelo at 5:25pm. And the latest bus departs at 5:40pm.
What are the CO₂ emissions for the bus trip from Madison to Tupelo?
A bus trip from Madison to Tupelo generates an estimated 25 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






