What is the travel distance from Palermo to Brindisi?

About 300 miles (483 km) separate Palermo and Brindisi.

What are the departure and arrival stations when taking the bus from Palermo to Brindisi?

The majority of buses traveling from Palermo to Brindisi start their journey at Terminal Bus Palermo and wind up at Brindisi Bus Stop. These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Brindisi?

Once in Brindisi, you can start exploring the city and discover its surroundings. The top sights and things to do are Swabian Castle of Brindisi, Ostuni, Lido Azzurro, Aragonese Castle and Brindisi Express - City Tour.

Bus Palermo to Brindisi from $97 | Refundable Tickets

Previously seen trips

Next departures for Palermo to Brindisi on November 20
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	4:30pm	Terminal Bus Palermo	1d 1h	5:49pm	Brindisi Bus Stop	No tags
Bus	4:30pm	Terminal Bus Palermo	23h 35m	4:05pm	Brindisi Bus Stop	No tags
Bus	4:30pm	Terminal Bus Palermo	23h 35m	4:05pm	Brindisi Bus Stop	No tags
Bus	4:30pm	Terminal Bus Palermo	1d 1h	6:25pm	Brindisi Bus Stop	No tags
Bus	4:30pm	Terminal Bus Palermo	23h 35m	4:05pm	Brindisi Bus Stop	No tags

Get from Palermo to Brindisi

This route is served by bus only

The journey takes about 23 hours 35 minutes and with fares starting at just $74, it presents an excellent value for a comfortable ride.

1bus per day

23h 35mAverage Duration

299 milesDistance

12kgCO₂ emissions

Compare bus companies

FlixBus

3.5/511,380 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Where are the popular stops in Palermo and Brindisi?

Stops in Palermo

A - Terminal Bus Palermo

B - Palermo Airport

C - Piazza Cairoli

D - Fiera

E - Via Paolo Balsamo, 21

F - Via Paolo Balsamo, 31

Stops in Brindisi

A - Brindisi Bus Stop

B - Brindisi Airport

C - Fermata dell'autobus Brindisi

D - Porto

E - Brindisi Rione Casale

F - Via Palmiro Togliatti

Frequently asked questions about traveling from Palermo to Brindisi by bus

What is the travel distance from Palermo to Brindisi?
What are the departure and arrival stations when taking the bus from Palermo to Brindisi?
What are the best sights and things to do in Brindisi?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/18

No data

11/19

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Today

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11/21

$97

11/22

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11/23

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11/24

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11/25

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The cheapest trip from Palermo to Brindisi was searched and found on Nov 21, 2025 with a price of $97

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Brindisi, as early as possible.

You can expect to pay from $97 to $97 for a bus ticket from Palermo to Brindisi based on the last 2 days. You can expect to find the cheapest price for the trip at $97 which is on 2025-11-21.