Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Bus Palermo | Brindisi Bus Stop | No tags | ||||
| Bus | Terminal Bus Palermo | Brindisi Bus Stop | No tags | ||||
| Bus | Terminal Bus Palermo | Brindisi Bus Stop | No tags | ||||
| Bus | Terminal Bus Palermo | Brindisi Bus Stop | No tags | ||||
| Bus | Terminal Bus Palermo | Brindisi Bus Stop | No tags |
Get from Palermo to Brindisi
The journey takes about 23 hours 35 minutes, and with fares starting at just $107, it presents an excellent value for a comfortable ride.
Where are the popular stops in Palermo and Brindisi?
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Stops in Brindisi
- AVia Giuseppe Maria Galanti, 8, 72100 Brindisi BR, Italy
- C
Fermata dell'autobus Brindisi
Viale Arno, 72100 Brindisi BR, Italy - D
Porto
Viale Regina Margherita, 72100 Brindisi BR, Italy - E
Brindisi Rione Casale
Via Osanna, 97, 72100 Brindisi BR, Italy - F
Via Palmiro Togliatti
Via Palmiro Togliatti, 11, 72100 Brindisi BR, Italy
Compare bus companies
Based on 11387 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $107
Frequently asked questions about travelling from Palermo to Brindisi by bus
What is the travel distance from Palermo to Brindisi?
The distance covered from Palermo to Brindisi is 483 km (300 miles).
What are the departure and arrival locations for buses traveling from Palermo to Brindisi?
Buses traveling this route start their trip at Terminal Bus Palermo, in Palermo, and end it at Brindisi Bus Stop, in Brindisi.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Brindisi was searched and found on Nov 21, 2025 with a price of $140To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Brindisi, as early as possible.
You can expect to pay from $140 to $140 for a bus ticket from Palermo to Brindisi based on the last 2 days. You can expect to find the cheapest price for the trip at $140 which is on 2025-11-21.
