Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Parcheggio Via Pietransantina | Gare routière de Gerland | Cheapest | ||||
| Bus | Parcheggio Via Pietransantina | Gare routière de Gerland | Fastest | ||||
| Bus | Parcheggio Via Pietransantina | Gare routière de Gerland | No tags |
Last refresh of the prices: Yesterday at 2:17 PM CEST.
Get from Pisa to Lyon
The journey takes about 13 hours 20 minutes and with fares starting at just $64, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Lyon?
Stops in Pisa
- B
Parcheggio Via Pietransantina
Via Pietrasantina, 56123 Pisa PI - C
Piazza della Stazione
Piazza della Stazione, 1, 56125 Pisa PI, Italy
Stops in Lyon
- B
Perrache
Rue de Esplanade, 69002 Lyon, France - C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - F
Les Charrières
Les Charrières, 69570 Dardilly, France
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Pisa to Lyon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pisa to Lyon?
The cheapest bus tickets from Pisa to Lyon start from $64. The average price for this route is around $103. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pisa to Lyon?
The average bus trip duration from Pisa to Lyon is 13h 20m, covering a distance of 306 miles (493 km). The quickest bus can get you there in 11h 45m and is operated by FlixBus.
Which bus companies service the Pisa to Lyon route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Pisa to Lyon?
The earliest bus departs from Pisa to Lyon at 5:45am. And the latest bus departs at 6:10pm.
What are the CO₂ emissions for the bus trip from Pisa to Lyon?
A bus trip from Pisa to Lyon generates an estimated 12.3061 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Lyon was searched and found on Jun 10, 2026 with a price of $81To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Lyon, as early as possible.
You can expect to pay from $81 to $101 for a bus ticket from Pisa to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $91 which is on 2026-06-14.
